旱莲草化学成分旱莲甙A和旱莲甙B的分离和鉴定  

ISOLATION AND IDENTIFICATION OF ECLIPTASAPONIN A AND ECLIPTASAPONIN B FROM ECLIPTA ALBA(L.)HASSK

作　　者：张梅[1] 陈雅妍[1] 

机构地区：[1]北京医科大学药学院,北京军区总医院药械科临床药理室

出　　处：《药学学报》1996年第3期196-199,共4页Acta Pharmaceutica Sinica

摘　　要：自旱莲草（Ｅｃｌｉｐｔａａｌｂａ（Ｌ．）Ｈａｓｓｋ）全草中分得４个三萜化合物，经理化常数测定和光谱（ＩＲ，ＭＳ，ＵＶ，１ＨＮＭＲ，１３ＣＮＭＲ和１３Ｃ－１ＨＣＯＳＹ）解析，２个已知的三萜类化合物分别为刺囊酸（ｅｃｈｉｎｏ－ｃｙｓｔｉｃａｃｉｄ，Ⅰ）和齐墩果酸（ｏｌｅａｎｌｉｃａｃｉｄ，Ⅱ），另２个为新化合物，分别命名为旱莲甙Ａ（ｅｃｌｉｐｔａｓａｐｏｎｉｎＡ，Ⅲ）和旱莲甙Ｂ（ｅｃｌｉｐｔａｓａｐｏｎｉｎＢ，Ⅳ）。Ⅰ和Ⅱ为首次从鳢肠属植物中获得。Two new triterpenoid glucosides ecliptasaponinA(Ⅲ)and ecliptasaponin B(Ⅳ)were isolated together with echinocystic acid(Ⅰ)and oleanic acid(Ⅱ) from Eclipta alba (L.)Hassk.Their structures were deduced as 3β, 16α-dihydroxy olean-12-ene-28-oic acid- 3β-O-D-glucopyra-noside(Ⅲ)and 3β-O-[β-D-glucopyranosyl( 1-4 )]-β-D-glucopyranosyl-16α-hydroxy olean-12-ene-28-oic acid 28-O-β-D-glucopyranoside(Ⅳ),based on spectral analysis and chemical evidences as wellas results of hydrolysis.

关 键 词：旱莲草 三萜皂甙 旱莲甙A 旱莲甙B 分离 鉴定 

分 类 号：R284.1[医药卫生—中药学]