新生儿重症高胆红素血症外周动静脉同步换血法应用研究  

The application of peripheral arterial and venous synchronous substitution transfusion to treat neonatal severe bilirubinemia.

作　　者：朱静秋[1] 温树才[1] 张怡[1] 杨丽萍[1] 谢晓玲[1] 

机构地区：[1]昆明市妇幼保健院新生儿科,云南昆明650031

出　　处：《云南医药》2005年第5期402-406,共5页Medicine and Pharmacy of Yunnan

摘　　要：目的探讨外周动静脉同步换血治疗新生儿重症高胆红素血症的疗效、安全性、适用性及对血液内环境的影响。方法采用股动脉、头皮静脉做换出、换入途径对15例重症高胆红素血症患儿进行同步换血,并对换血前后及换血后24h的多项指标进行监测。结果换血后总胆红素、间接胆红素明显下降(P<0.001),内环境影响小,多数变化指标换血24h内恢复或有不同程度回升。结论外周动静脉同步换血法疗效肯定,无明显并发症,值得推广。To observe the effect, safety degree, adaptability and influence on the environment of blood circulation in treating severe bilirubinemia of newly - born infants with peripheral arterial and venous synchronous substitution transfusion. Method 15 cases with severe bilirubinemia were subjected to this transfusion, with their arteria femoralis and scalp veins used as inlets and outlets for this simultaneous transfusion, some indice and data were monitored and observed closely before and 24 hours after the transfusion. Result Both the total and indirect bilirubin dropped significantly after the transfusion （P 〈 0.001）. It hardly disturbed the infants＇ internal environment, and most of the indice recovered and restored to better condition within 24 hours after the transfusion. Conclusion Peripheral arterial and venous synchronous substitution transfusion has definite effect. It is easy to operate, and is safe, time - saving and adaptable, with no obvious complications. Widespread of this trnsfusion is recommended.

关 键 词：外周动静脉 换血 新生儿 效果 安全性 

分 类 号：R722.18[医药卫生—儿科]