常用微循环研究部位的肽能和胺能神经分布的比较  

COMPARATIVE STUDY ON THE PEPTIDERGIC AND SEROTONINERGIC INNERVATION IN DIFFERENT HISTOLOGIC REGLONS COMMONLY USED FOR MICROCIRCULATION STUDIES

作　　者：张励才 王梅申 朱治远 张风真 

出　　处：《徐州医学院学报》1996年第2期133-136,共4页Acta Academiae Medicinae Xuzhou

基　　金：江苏省教委自然科学基金

摘　　要：以ＣＢ－ＨＲＰ逆行追踪与ＰＡＰ免疫细胞化学法相结合，比较了降钙素基因相关肽（ＣＧＲＰ）、神经肽Ｙ（ＮＰＹ）、甲啡肽（Ｍ－ＥＮＫ）和５－羟色胺（５－ＨＴ）等肽能和胺能递质在支配提睾肌、盲肠系膜和耳廓等微循环研究常用部位的神经元内的分布。结果表明：上述肽能和胺能递质在支配不同部位的运动、感觉和交感节后神经元内的分布具有明显的差异。由于本实验所用的实验部位提睾肌、盲肠系膜和耳廓在组织学上分别以骨骼肌、间皮和软骨为主要成分构成的。因此，造成这种差异的原因是否与这些神经所支配的部位在组织学上具有明显的不同有关，值得思考。The intraneuronic distribution of peptidergic transmitter (NPY, CGRP,M－ENK) and serotoninergic transmitter(5-HT) in the nerves that innervate the commonly-used regions for microcirculatory studies were studied in rats by using combined CB-HRP and PAP methods,The examined regions are of different histologic natures,i.e,the skeletal-muscular cremaster, the mesothelial mesocecum and the cartilaginous auricle.The results revealed a great diversity among the patterns of intraneuronic distribution of the transmitters in the motor, sensory and post-ganglionic sympathetic nerves that innervate the separate regions.It is postulated that the diversity of transmitter distribution be related to the varied histologic natures of the examined regions.

关 键 词：微循环 神经支配 肽能 胺能 

分 类 号：R331[医药卫生—人体生理学]