氯胺酮、安氟醚麻醉对子宫切除术患者血浆心钠素、肾素、血管紧张素和醛固酮的影响  

Effect of Ketarmine-Enflurane Anesthesia on the Levels of Plasma Atrial Natriuretic Peptide, Renin Activity, Angiotensin and Aldosterone in Patients Undergoing Hysterectomy

作　　者：马占文[1] 王天元[1] 姜亚昌 

机构地区：[1]白求恩医科大学第三临床学院麻醉科,长春市邮政编码130021 [2]四平市卫生学校附属医院

出　　处：《临床麻醉学杂志》1996年第2期87-89,共3页Journal of Clinical Anesthesiology

摘　　要：本文研究了氯胺酮、安氟醚麻醉对子宫肌瘤切除术患者血浆心钠素(ANP)、肾素(PRA)、血管紧张素(AⅡ)和醛固酮(AL)水平的影响。通过15例子宫肌瘤切除术患者的临床观察,结果表明,子宫肌瘤手术患者氯胺酮、安氟醚麻醉后10min、30min、1h和术毕ANP显著高于麻醉前(P<0.05);PRA与麻醉前比较有升高趋势;AⅡ在麻醉后30min至术毕显著低于麻醉前(P<0.05);血浆AL自麻醉后10min开始升高,至麻醉后1h和术毕非常显著升高(P<0.01)。本文还讨论了它们之间的相互关系。The effect of the ketamine,enflurane anesthesia on the levels of plasma atrial natriuretic peptide(ANP) , renin activity (PRA). angiotensin I (A I ) and aldosterone(AL) was studied in 15 patients of hysterectomy. Results show that the levels of ANP tested at 10 min, 30 min, 60 min after ketamine-enflurane ansthesia and at the end of operation were significantly higher than that before anesthesia (P<0. 05). PRA tended to rise as compared with that before anesthesia. From 30 minutes after anesthesia to the end of operation A I were lower than that before anesthesia (P<0. 05). Plasma AL began to rise at 10 min after anesthesia, and increase significantly at 60 min after anesthesia till the end of operation, as compared with that pre-anesthesia (P<0. 01). Their correlations were discussed.

关 键 词：子宫切除术 心钠素 肾素 血管紧张素 醛固酮 

分 类 号：R713.42[医药卫生—妇产科学]