无创持续气道正压通气治疗新生儿早期呼吸障碍  

Study on the early intervention of nasal continuous positive airway pressure ventilation for newborn respiratory disorder

作　　者：严越秀[1] 莫伟雄[1] 张小玲[1] 乔萍[1] 肖力[1] 汪江萍[1] 

机构地区：[1]肇庆市第一人民医院儿科,广东肇庆526021

出　　处：《中国基层医药》2005年第10期1385-1386,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的观察无创持续气道正压通气(NCPAP)治疗新生儿早期呼吸障碍的有效性及安全性.方法应用NCPAP治疗新生儿早期呼吸障碍25例,分析应用前后心率、呼吸、经皮血氧饱和度、动脉血气变化.结果 21例患儿于24～48 h呼吸频率明显恢复正常(P＜0.05),呼吸障碍明显缓解,且均治愈;3例因肺透明膜病加重转为机械通气.膈神经损伤1例自动出院.结论 NCPAP早期治疗因肺泡萎陷、低通气所致的呼吸障碍是安全有效的.Objective To study the effect and safety of nasal continuous positive airway pressure（NCPAP） in the treatment of early respiratory disorders in newborn. Methods 25 newborns with early respiratory disorders were treated with NCPAP, the change of heat rhythm （HR）, respiratory, transcutaneous oxygen saturation（SpO2 ） and blood gas were dialysed before and after treatment. Results After the treatment with NCPAP,the respiratory rate of 21 patients significantly recovered to normal in 24- 28 hours（ P 〈 0.05 ）, the respiratory disorder was remission, and all patients were cured; Hyaline membrane disease of 3 patients aggravated and the patients were treated with mechanical ventilation,and one patients with phrenic nerve injury discharged by himself. Conclusion The NCPAP is safe and effective in the treatment of respiratory disorders caused by alveolar collapse and low ventilation.

关 键 词：正压呼吸 呼吸障碍 婴儿 新生 持续气道正压通气 正压通气治疗 新生儿 早期 无创 NCPAP治疗 经皮血氧饱和度 

分 类 号：R722.1[医药卫生—儿科]