小儿围体外循环期血浆离子钙浓度的变化  

Changes of Plasma Ionised Calcium Concentration in Children Undergoing Gardiopulmonary Bypass

作　　者：王涛[1] 张善通[1] 曹金红[1] 王人荣[1] 

机构地区：[1]上海医科大学儿科医院心血管中心

出　　处：《中华胸心血管外科杂志》1996年第3期152-153,共2页Chinese Journal of Thoracic and Cardiovascular Surgery

摘　　要：为研究小儿围体外循环期血浆离子钙浓度的变化规律，指导临床合理地应用钙剂，连续测定了６０例先天性心脏病病儿血浆离子钙浓度［Ｃａ２＋］、ｐＨ、红细胞压积（ＨＣＴ）。结果表明，在ｐＨ相对恒定的情况下，［Ｃａ２＋］在转流１５分钟时最低，此后逐步升高，转流后２小时同转流前、２４小时与４８小时高于转流前水平。转流中的［Ｃａ２＋］经ＨＣＴ校正后明显高于转流前。婴幼儿与年长儿、紫绀组与非紫绀组之间无差异。结论：小儿围体外循环期有内源性［Ｃａ２＋］产生，一般无需补充钙剂。Aim:This study was designed to observe the aiteration of plasma ionised calcium concentration [Ca2+] in children undergoing cardiopulmonary bypass(CPB).Materials and Methods:The[Ca2+],pH and hematocrit were assayed in 60 patients with congenital heart diseases.Results:The results showed that the level of[Ca2+]was lowest at l5 minutes after the start of CPB,then elevated gradually,and finally returned to the pre-bypass leve l2 hours after the termination,and to a higher lewel 24 hours and 48 hours post-CPB. But,the corrected value of [Ca2+] by hematocrit during CPB was significantly higher than that of pre-CPB.Conclusion:Because of endogenous release of [Ca2+]our daba indicate that it is nor necessary to supple calcium salt during and after CPB because of the preseuce of endogenous release of[Ca2+]。

关 键 词：血浆 离子钙 体外循环 

分 类 号：R654.1[医药卫生—外科学]