阿魏酸钠治疗老年人不稳定型心绞痛临床疗效分析  

A clinical observalion on the thesapeutic effect of sodium ferulate in the elderly patients with unstable angina

作　　者：金明磊[1] 赵晓玲[1] 王乃梅[1] 

机构地区：[1]河北省承德市中心医院干部外宾病房,067000

出　　处：《实用心脑肺血管病杂志》2005年第6期326-328,共3页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的观察注射用阿魏酸钠(SF)治疗不稳定型心绞痛在老年人群中临床疗效与安全性。方法不稳定型心绞痛62例随机分为对照组30例,观察组32例。对照组与观察组均予硝酸脂类、β-受体阻断剂、血管紧张素转换酶抑制剂、阿司匹林、低分子肝素等常规治疗。观察组加用阿魏酸钠300mg+5%葡萄糖250ml静脉滴入;对照组加用复方丹参注射液12ml+5%葡萄糖250ml静脉滴入,每日一次,以14天为1个疗程进行疗效比较。结果观察组总有效率78·1%,对照组53·3%,两组比较差异有显著性(P<0·05)。结论注射用阿魏酸钠治疗不稳定型心绞痛在老年人群中疗效显著、副作用小。Objective To explore the therapeutic effect and safety of Sodium ferulate in the elderly patient with unstable angina. Methods 62 patients with unstable angina were randomly divided into two groups. The patients in the Sodium ferulate group（ n = 32） ,were given sodium ferulats 300mg ＋ 5% glucose solution 250ml by IV infusion qd. besides routine treatment and the control group （ n = 30 ） only was routine treatment. After 2 weeks the clinical effect, biochemical parameters and side reactions were observed in all the patients. Results The overal effective rate in the Sodium ferulate group was 78. 1% ,and 53.3% in the control group. There were significant difference between the two groups（ P 〈0.05）. Conclusion The Sodium ferulate is an effective and safe drng for treatment of unstable angina in the elderly.

关 键 词：不稳定型心绞痛 注射用阿魏酸钠 老年 老年人不稳定型心绞痛 临床疗效分析 常规治疗 血管紧张素转换酶抑制剂 Β-受体阻断剂 复方丹参注射液 5%葡萄糖 

分 类 号：R541.405[医药卫生—心血管疾病] R286.8[医药卫生—内科学]