回春汤对D-半乳糖衰老模型小鼠抗氧化系统的影响  

Effect of Huichun Decoction on Antioxidation of Aging Mice Induced by D-galactose

作　　者：谷建云[1] 谭兴贵[1] 阳力争[1] 于雅婷 孙桂香[1] 

机构地区：[1]湖南中医学院,2002级研究生班湖南长沙410007 [2]吉林省中医院,吉林长春130021

出　　处：《湖南中医学院学报》2005年第5期16-17,34,共3页Journal of Hunan College of Traditional Chinese Medicine

基　　金：湖南省教育厅课题(04C424)

摘　　要：目的探讨回春汤对D—半乳糖衰老模型小鼠抗氧化系统的影响。方法将小鼠随机分为空白组、衰老模型组、维生素E组、回春汤大、小剂量组5组,采用灌胃给药6周后测定指标。选用:血浆丙二醛(MDA)含量、红细胞超氧化物歧化酶(SOD)活力、肝组织谷胱甘肽过氧化物酶(Gsh—Px)活力为指标,观察回春汤对D—半乳糖衰老模型小鼠抗氧化系统的影响。结果回春汤2个剂量组均能提高D—半乳糖所致衰老小鼠的红细胞SOD活力、肝组织谷胱甘肽过氧化物酶(GSH—PX)活力,降低血清MDA含量。结论回春汤具有良好的抗氧化作用,有助于延缓衰老过程。Objective To observe the antioxidation of Huichun decoction on aging mice induced by D-galactose. Methods Mice were divided into blank contrast, aged model, positive control（Vit-E）, Huichun decoction large dose and middle-dose groups,all which will be fed in six weeks, MDA,SOD,GSH-PX were chose as targets to observe the effect. Results In Huichun decoction treating groups, SOD and GSH-PX were incrased and MDA was decreased. Conclusion Huichun decoction has good effects in antioxidation and postponing aging process.

关 键 词：回春汤 衰老 D-半乳糖 小鼠 抗氧化作用 

分 类 号：R285.5[医药卫生—中药学]