早期血液学检查在重症SARS病人早期预警中的应用  

Early blood and serological enzyme examination using in early signal of diagnosis of severe cases SARS

作　　者：杜惠芳[1] 刘思志[1] 李奕民[1] 杨哲[1] 赵建元[1] 

机构地区：[1]广东省广州市第一人民医院病案统计科,广东广州510180

出　　处：《世界感染杂志》2005年第5期386-388,共3页World Journal of Infection

摘　　要：目的 分析284例重症SARS（严重急性呼吸综合征）病人入院后7d的生化和血液学检查。方法 用回顾性的方法对284例重症SARS病例入院1wk内的生化和血液学检查资料进行分析。结果 重症SARS病人入院后1wk内40．2％的病人淋巴细胞低于正常。BUN，Cr有22．1％和6．2％增高。重症病人的ALT，AST有70．9％和53．0％增高，LDH，CK，CK-MB有80．1％、31．9％和25．6％出现增高，经过统计学分析均与轻症组有显著性差异。结论 重症SARS病人病程早期出现淋巴细胞计数降低，并且有相当一部分病人出现肝肾功能异常和血清酶系统异常，通过以上指标可以较准确的对可能发生病情加重进行早期预警。Objective To investigate the features of the blood routine examination and serological enzyme examination of the 284 cases with severe Severe Acute Respiratory Syndrome （SARS）. Methods The blood routine examination and serological enzyme examination data of 284 cases of severe SARS in hospitalized one week with SARS in 2003 were retrospectively analyzed. Results Low lymphocyte count was found in 40.2%. BUN, Cr was found increased to abnormality in 22.1% and 6.2%, ALT, AST was found increased to abnormality in 70.9% and 53.0%, and LDH, CK, CK-MB was found increased to abnormality in 80.1%, 31.9% and 25.6%, significant difference was found while compared with minor patients. Conclusion The patients with severe SARS have lower values of lymphocyte in the early stage. Some of them even presented with abnormal changes in the liver function and enzyme system. The lymphocyte count examination and serological enzyme examination were early signal in the early diagnosis of severe SARS.

关 键 词：SARS 重症 血液学 早期诊断 

分 类 号：R563.1[医药卫生—呼吸系统] R331.14[医药卫生—内科学]