壳寡糖冲剂治疗固定正畸中牙龈炎30例  

Therapeument of Chitooligosaccharide in 30 Patients with Gingivitis in Fixed Orthodontics

作　　者：龙小斯[1] 凌慧[1] 沈真祥[2] 

机构地区：[1]华中科技大学同济医学院附属协和医院口腔正畸科,武汉430022 [2]武汉大学口腔医院口腔正畸科,武汉430070

出　　处：《医药导报》2005年第11期1011-1012,共2页Herald of Medicine

摘　　要：目的探讨壳寡糖对固定正畸中牙龈炎的治疗效果.方法 12～20岁临床固定正畸患者60例,随机分为治疗组和对照组,治疗组30例在固定正畸后即开始含漱并冲服壳寡糖冲剂,每次0.4 g,bid,连续服用4周;对照组30例不使用任何药物.记录两组治疗前及治疗开始后2,4周的牙周指数(包括牙龈指数、菌斑指数、简易牙石指数等)并进行组间比较.结果与治疗前相比,治疗组患者的牙龈指数在治疗开始后2,4周分别降低了28.8%,32.9%;菌斑指数分别降低了32.3%,34.7%;简易牙石指数变化不明显.对照组以上指标无明显变化.治疗组患者的牙龈指数、菌斑指数在治疗开始后2,4周均明显低于对照组(均P＜0.01).结论壳寡糖治疗固定正畸中牙龈炎疗效显著.Objective To study the effects of chitooligosaccharide on gingivitis in fixed orthodontics. Method 60 fixed orthodontic patients were randomly divided into treatment group and control group. Chitooligosaccharide was orally given to the treatment group, nothing to the control group. Gingival index （GI）, plague index （PLI） and simple calculas index （CI-S） were measured and compared before and after treatment. Results After treatment for 2, 4 weeks, GI in the treatment group were significantly decreased 28.8%, 32.9% ; and PLI 32.3%, 34.7%, than in the control group （ P 〈 0.01 ）. But the CI-S had no change. Conclusion Chitooligosaccharide is effective in the treatment of gingivitis in fixed orthodontics.

关 键 词：壳寡糖 固定正畸 牙龈炎 

分 类 号：R988.2[医药卫生—药品] R781.4[医药卫生—药学]