抗血小板药物中断对缺血性中风的影响  

作　　者：储旭华[1] 顾成龙[1] 厦新宇[1] 

机构地区：[1]南京医科大学第一附属医院神经内科,210029

出　　处：《脑与神经疾病杂志》2005年第5期354-355,共2页Journal of Brain and Nervous Diseases

摘　　要：目的：研究APD中断对中风的影响。方法：在连续的住院患者中，调查APD中断后缺血性中风患者APD中断的原因，中风的机制以及中风发作的潜伏期。结果：在289例缺血性中风患者中，4．49％有APD中断，ADP中断与中风起病的潜伏期为7．4±1．26天。结论：部分缺血性中风的发病与ADP中断有关。在带有多种血管病危险因子的人群中，ADP中断是缺血性中风的一个高危因素。Objective： To study APD discontinuation＇s influence on stroke. Methods： The authors studied the frequency of stroke occurring after APD discontinuation, the cause of discontinuation, and the delay between APD disruption and stroke. Results： in 289 cases of ischemic cerebrovascular diseases, 4.49 % of strokes were related to a recent APD discontinuation, but all cases occurred between 6 and 10 days after drug discontinuation. Conclusions： the part of ischemic cerebrovascular disease cases is associated with APD discontinuation, the delay between APD disruption and stroke ADP is 7.4±1.26 days. This temporal pattern has biologic plausibility because the inhibited platelets circulate in the blood for about 10 days.

关 键 词：APD中断 缺血性脑血管病 血小板 缺血性中风 药物中断 抗血小板 中风患者 APD ADP 住院患者 

分 类 号：R255.2[医药卫生—中医内科学] R963[医药卫生—中医学]