东莞地区新生儿听力筛查的多中心研究  

Multicenter study of neonatal hearing screening in Dongguang region

作　　者：彭倩[1] 何锐志[1] 胡满和[1] 张肖娟[1] 黄见可 陈就好[3] 陈彩凤[3] 张俭 邵秀敏 吴秀兰[5] 严薇 朱惠春 

机构地区：[1]东莞市妇幼保健院 [2]东莞市石碣人民医院 [3]东莞市太平人民医院 [4]东莞市清溪医院 [5]东莞市莞城医院 [6]东莞市凤岗医院 [7]东莞市水电三局医院,广东东莞532002

出　　处：《中国当代儿科杂志》2005年第5期459-460,462,共3页Chinese Journal of Contemporary Pediatrics

基　　金：东莞市科技局立项课题(编号2004-40)

摘　　要：目的探索适合于新生儿听力筛查的临床策略,通过多中心合作获得新生儿听力损失发病的基本资料。方法应用畸变产物耳声发射技术(DPOAE)进行听力普遍筛查。对复筛未通过者,于生后3个月左右采用听性脑干反应(ABR)和40Hz听性相关电位(40HzAERP)技术诊断。结果该研究实际筛查17360例,筛查率为89.1%。初筛通过15624例(90.0%)。需复筛的1736例,实际复筛1597例,复筛率92%,复筛通过1491例,复筛通过率93.4%。41例复查ABR其中确诊新生儿先天性听力损失39例,减去2例假阳性,该组新生儿先天性听力损失的发生率为2.25‰。结论新生儿听力普查十分必要。DPOAE是一种快速行之有效的新生儿听力初筛方法,两步筛查法可及早发现听力损失,听力筛查、诊断、康复统筹运作是使聋儿得以康复的重要保证。Objective This study performed muhicenter neonatal heating screening in the Dongguang region so as to explore the model of neonatal hearing screening suitable for this region. Methods The study population consisted of 17 360 infants from 6 hospitals of Dongguang region. Universal heating screenings by distortion product otoacoustic emission （DPOAE） techniques were done within 24- 48 hrs after birth. Infants who failed the initial screening test underwent second screening by DPOAE one month later. Acoustic brain-stem response （ABR） and 40 Hz auditory event related potential （40Hz-AERP）techniques were used to examine the hearing of those who failed the second heating screening test at age of 3 months. Results Of the 17360 infants, 15 624 （89.1%）passed the initial screening. A total of 1736 cases needed a second screening test. One thousand five hundred and ninety seven infants underwent the second test. Among the 1597 cases, 1491 （93.4%） passed the second screening. Ultimately 39 cases were diagnosed with congenital hearing loss, with an incidence of heating loss of 2.25‰. Conclusions DPOAE can be used as a rapid and effective method for initial hearing screening in infants. The two-stage heating screening test can identify heating loss early.

关 键 词：听力筛查 多中心研究 新生儿 

分 类 号：R764[医药卫生—耳鼻咽喉科]