HPLC法对儿乐康口服液中橙皮苷含量的测定  

HPLC Determination of Content of Aurantiamarin in Erlekang Oral Liquid

作　　者：宋福坤 赵勤[2] 邢卫[1] 

机构地区：[1]江苏省苏州市第二人民医院,江苏苏州215002 [2]江苏省苏州市药品检验所,江苏苏州215002

出　　处：《南京中医药大学学报》2005年第6期384-385,共2页Journal of Nanjing University of Traditional Chinese Medicine

摘　　要：目的建立HPLC法测定儿乐康口服液中橙皮苷含量的方法.方法采用VP-BDS色谱法,检测波长为284 nm,为流动相,乙腈-水-磷酸(20:79.8:0.2).结果橙皮苷在0.288～1.440μg范围内呈良好线性关系(r=0.999 5),平均回收率为98.6%(RSD=1.03%,n=5).结论本法操作简便,结果准确,重现性好、稳定,可用于该制剂的质量控制.OBJECTIVE To establish HPLC determination method for the content of aurantiamarin Erlekang Oral Liquid. METHOD VP- BDS chromatography （detection wavelength： 284nm; acetonitrile- water- phosphoric acid at the ratio of 20：79.8 ：0.2 as the mobile phase） was adopted. RESULT Within the range of 0.288 - 1.440/lg, aurantiamarin assumed fine linear relation （ r = 0.999 5）, the average recovery rate was 98.6 %, RSD = 1.03 %. CONCLUSION This method is simple, stable and accurate with fine reproducibility, and can be used in the quality control of the product.

关 键 词：儿乐康口服液 橙皮苷 高效液相色谱法 

分 类 号：R284.1[医药卫生—中药学]