水蛭提取液对凝血酶诱导的视网膜色素上皮细胞增殖的影响  

Effect of hirudinoid extract on retinal pigment epithelium for proliferation induced by thrombin

作　　者：郑燕林[1] 王明芳[1] 盛蓉[1] 陈海燕[1] 吕帆[1] 

机构地区：[1]成都中医药大学附属医院眼科

出　　处：《中国中医眼科杂志》2005年第4期199-201,共3页China Journal of Chinese Ophthalmology

基　　金：国家自然科学基金资助(30371796)

摘　　要：目的观察渗滤法水蛭提取液对体外培养视网膜色素上皮细胞(retinal pigment epithelium,RPE)增殖的影响。方法利用体外培养的视网膜色素上皮细胞,观察水蛭提取液对凝血酶诱导的视网膜色素上皮细胞增殖的影响。结果128mg/ml水蛭提取液对体外培养的视网膜色素上皮细胞具有抑制增殖的作用。结论水蛭提取液对体外培养的视网膜色素上皮细胞具有抑制增殖的作用。OBJECTTVE To observe effect of hirudinoid extract by percolation leech on proliferation of retinal pigment epithelium （RPE） cultured.METHODS Use retinal pigment epithelium culture in vitro, to observe effect of hirudinoid extract on retinal pigment epithelium for proliferation induced by thrombin. RESULTS 128mg/ml hirudinoid extract can inhibit proliferation of retinal pigment epithelium cultured in vitro. CONCLUSIONS Hirudinoid extract can inhibit proliferation of retinal pigment epithelium cultured in vitro.

关 键 词：水蛭 视网膜色素上皮细胞 凝血酶 

分 类 号：R285.5[医药卫生—中药学]