加味逍遥散的三维高效液相色谱法鉴定和指标成分的定量  

The Identification and Determination of Marker Substance in Jawei Xiaoyao San by Three Dimensional HPLC

作　　者：陈发奎[1] 郭允珍[1] 鹿野美弘[1] 

机构地区：[1]沈阳药学院,日本国北海道药科大学

出　　处：《药物分析杂志》1996年第1期22-26,共5页Chinese Journal of Pharmaceutical Analysis

摘　　要：本文报道用三维高效液相色谱法对加味逍遥散中单味药进行定性鉴定，并对其中所含柴胡皂甙、山栀子甙等８种指标成分进行了含量测定，均得到满意结果。A Chinese traditional patent medicine Jiawei Xiaoyao San was analysed by three dimensional HPLC. The result shows that the Chinese medicine involved in Jiawei Xiaoyao San was identified excellently and the content of Marker substance can be determined. According to the results of determination, the percent content of saikosaponin b1, b2 glycyrrhizin, paeonol, paeoniflorin, geniposide, atractylenolide Ⅲ and 6-gingerol in Jiawei Xiaoyao San was 1.08 (mg/d) 0.71, 76.13, 2.76, 78.43, 63.25, 0.46 and 12.42, respectively. The average relative standard deviation was 1.4%, 3.6%, 1.2%, 0%, 1.5%, 1.0%, 0% and 3.4% respectively.

关 键 词：加味逍遥散 高效液相色谱法 指标成分 

分 类 号：R289.5[医药卫生—方剂学]