五灵脂对胃粘膜保护作用的临床与实验研究  

Clinical and Experimental Study of Faeces Trogopterus on Protection of Gastric Mucosa

作　　者：李庆明[1] 

机构地区：[1]中山医科大学孙逸仙纪念医院

出　　处：《中国中西医结合杂志》1996年第2期90-92,共3页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：用五灵脂治疗３４例十二指肠溃疡病患者，６周为１个疗程。结果：痊愈率７０．５９％，总有效率９１．１８％。通过大白鼠Ｓｈａｙ模型动物实验，结果表明五灵脂对胃粘膜有保护作用。可能的作用机制是抑制胃液胃酸分泌，以及调节改善胃粘膜血流，增加胃粘膜的防御功能。The cure rate of Faeces Trogopterus in treating duodenal ulcer for six weeks was 70.59% and the total effective rate of which was 91.18%.The Shay model of rats was used.The result revealed that Faeces Trogopterus could protect the gastric mucosa.These results preliminarily indicated the mechanism of this drug was inhibiting gastric secretion and regulating gastric mucosal blood flow so as to enhance mucosal defense.

关 键 词：五灵脂 胃泌素 胃粘膜血流 十二指肠溃疡 药理 

分 类 号：R282.740.5[医药卫生—中药学]