硒对氟在大鼠体内蓄积、排泄的影响  

Effects of selenium onbody accumulation and urinary excretion of fluorideiu rats.

作　　者：杨成峰[1] 陈学敏[1] 吴建平[1] 

机构地区：[1]同济医科大学环境卫生学教研室

出　　处：《职业医学》1996年第1期2-3,共2页China Occupational Medicine

摘　　要：通过饮水加氟（Ｆ５０ｍｇ／Ｌ）或／和加硒（Ｓｅ０．５ｍｇ／Ｌ）的方法，研究了硒对氟在大鼠体内蓄积、排泄的影响。结果表明饮水加氟可使大鼠血清氟、骨氟含量及尿氟排泄量显著增加；饮水同时加硒可显著降低氟中毒大鼠血清氟含量，但对大鼠骨氟含量、尿氟排泄量无显著影响。he effect of selenium on body accumulation andurinary excretion of fluoride in rats was studied byadding fluoride(50mg/L)or/and selenium(0.5mg/L)to drinking water.The results showed that fluo-ride added to drinking water could significantly in-crease the contents of fluoride in serum, bone andurine, Whereas,the content of fluoride in serum wasdecreased significantly by adding selenium to drinkingwater simultaneously. However,the contents of fluo-ride in bone and urine were not affected obviously byadding selenium to drinking water.

关 键 词：氟 硒 拮抗作用 氟中毒 

分 类 号：R135.1[医药卫生—劳动卫生]