嗜肺军团菌对人体中性粒细胞NBT还原作用的影响  

Effect of legionella pneumophila on NBT reduction of human neutrophils

作　　者：王桂琴[1] 谢皙子[1] 郭淑清[1] 陈明 

机构地区：[1]山西医学院微生物学教研室,太原030001 [2]太原钢铁公司尖草坪医院

出　　处：《中华微生物学和免疫学杂志》1996年第1期22-24,共3页Chinese Journal of Microbiology and Immunology

基　　金：本研究受国家自然科学基金资助

摘　　要：以ＮＢＴ还原试验微量比色法测定嗜肺军团菌对人体中性粒细胞氧化代谢的影响，发现经洗涤的活菌能激发嗜中性多形核白细胞（ＰＭＮ）的ＮＢＴ还原作用，而细菌培养物滤液在对ＰＭＮ无细胞毒性的浓度表现抑制ＮＢＴ还原的效应。The effect of Legionella pneumophila on the oxidative metabolism of human neutrophils was demonstrated with a colorimetric microssay for NBT reduction. The results showed that the reduction of NBT of PMN was activated by the washed viable bacterial cells but inhibited by the culture filtrate at a concentration that had no cytotoxic effect on PMN.

关 键 词：嗜肺军团菌 NBT还原试验 中性粒细胞 

分 类 号：R378[医药卫生—病原生物学]