异丙酚麻醉用于胃镜检查的临床研究  

Study on painless gastroscopy with propofol

作　　者：罗其泰[1] 邱春雷[1] 黄文武[1] 龚国华[1] 

机构地区：[1]江西省井冈山学院附属医院,吉安343000

出　　处：《江西医药》2005年第10期607-609,共3页Jiangxi Medical Journal

摘　　要：目的研究异丙酚麻醉用于胃镜检查的镇静效果和安全性。方法胃镜检查患者65例给予异丙酚镇静,110例予常规操作(不给予任何镇静药),比较2组胃镜检查中患者反应和感受、操作时间,观察其清醒时间及检查前、中、后的血压、心率及血氧饱和度的变化。结果无不适感率镇静组为96.9%,对照组为35.5%(P<0.01);镇静组患者咳嗽、呃逆、恶心呕吐和咽喉部不适的发生率分别为3.1%、1.5%、1.5%、0%,明显低于对照组(分别为7.3%、7.3%、48.2%、67.3%,P<0.01);镇静组胃镜操作时间为(4.1±1.2)min,短于对照组(5.3±1.7)min,(P<0.01)。镇静组患者清醒时间为(2.1±1.9)min,检查中有血压下降,但检查结束后迅速恢复检查前水平。结论胃镜检查时适量应用异丙酚镇静,是一种安全、有效的方法。Objective To study the efficacy and safety of sedation for gastroscopy with propofol. Methods Sixty-five patients in sedative group were given intravenous propofol. Patient＇s feeling and discomfort,operator＇s satisfaction and operative duration were compared with the control group （n=110,without sedation）.The changes of blood pressure,heart rate and blood oxygen saturation were recorded and analysed. Results Sixty-four patients（96.9%） in sedative group and thirty-nine patients（35.5%） in control group did not complain any discomfort and pain during gastroseopy （P〈0.01）.The incidence of cough,hiccup,nausea and vomitig,and guttural discomfort in sedative group（3.1%,1.5%,1.5% and 0%,respectively） was lower as compared with the control group（7.3%,7.3%,48.2% and 67.3%, respectively ,P〈0.01 ）.The operative duration of sedative group was shorter than that of control group （P〈0.01）.The recovery time of sedative group was（2.1±1.9）minutes.The blood pressure in sedative group was decreased during the procedure and recovered after the procedur.Conclusion With intravenous use of propofol, gastroscopy can be performed effectively and safely.

关 键 词：异丙酚 胃镜检查 麻醉 

分 类 号：R971.2[医药卫生—药品]