急性冠状动脉综合征患者血清胆红素及血脂水平的性别差异  

The Gender-related Differences of Serum Bilirubin and Lipid Concentrations in the Patients with Acute Coronary Syndromes

作　　者：孟海燕[1] 王少媛[2] 张奇志[1] 朱蕾[2] 张琴[1] 王磌[1] 

机构地区：[1]山东省交通医院心内科,济南市250031 [2]山东省交通医院普内科,济南市250031

出　　处：《中国交通医学杂志》2005年第5期444-445,共2页Chinese Medical JOurnal of Communications

摘　　要：目的:观察不同性别急性冠脉综合征(ACS)血清胆红素、血脂水平及临床表现差异。方法:对ACS患者男198例,女164例,健康对照组男36例,女34例,测定清晨空腹血清直接胆红素(DBi)、间接胆红素(IDBi)、总胆红素(TBi)、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)和高密度脂蛋白胆固醇(HDL-C)水平。结果:无论男女,ACS患者DBi、IDBi、TBi水平明显低于对照组(P<0.05),TC、TG、LDL-C均高于对照组(P<0.05)。ACS男性患者DBi、IDBi、TBi、HDL-C显著低于女性患者(P<0.05),而TC、TG、LDL-C水平高于女性(P<0.05)。而对照组男女间上述指标无统计学差异。结论:综合分析血清胆红素、血脂水平有助于预测ACS的发生,尤其有利于男性ACS预测。Objective：The aim of this study was to determine the gender- related differences of serum bilirubin and lipid concentrations in the patients with acute coronary syndromes（ACS）. Methods： The serum concentrations of directed-bilirubin, indirected- bilirubin, total- bilirubin, total cholesterol , triglyceride, low- density lipoprotein cholesterol and highdensity lipoprotein cholesterol were measured with automatic biochemic analytical instrument. Results：The serum concentrations of bilirubin in men was lower than in women with acute coronary syndromes, but total cholesterol , triglyceride, lowdensity lipoprotein cholesterol and high-density lipoprotein cholesterol were higher than in women. Conclusions： Aggregate analysis with serum bilirubin and lipid concentrations will profit to predict the occurrence of acute coronary syndromes, espscially for males.

关 键 词：急性冠脉综合征 胆红素 脂质 

分 类 号：R541.4[医药卫生—心血管疾病]