微创穿刺联合β-七叶皂甙治疗55例重型高血压性脑出血  

Treatment of severe hypertensive intracerebral hemorrhage by minimally invasive puncture combined with administration of β-aescine sodium: A clinical experience of 55 cases

作　　者：鲍建洲 周宝花 

机构地区：[1]山东省东营市第二人民医院神经科,东营257335

出　　处：《中国微创外科杂志》2005年第11期940-942,共3页Chinese Journal of Minimally Invasive Surgery

摘　　要：目的探讨重型高血压性脑出血的有效救治方法。方法回顾性分析我院1997年5月～2003年12月110例重型高血压性脑出血,按治疗方法分为2组,保守组(对照组)应用内科保守治疗措施,微创组应用微创穿刺、尿激酶灌注引流联合β-七叶皂甙静脉滴注等综合措施治疗。结果微创组55例中,显效率81.8%(45/55),总有效率89.1%(49/55),病死率10.9%(6/55)。对照组55例中,显效率32.7%(18/55),总有效率49.1%(27/55),病死率43.6%(24/55)。微创组疗效优于保守组(χ2=20.604,P=0.000)。结论微创穿刺、尿激酶灌注引流联合β-七叶皂甙静脉滴注等综合措施治疗重型高血压性脑出血简单、安全、有效、并发症少,能显著改善病人的预后。Objective To investigate the treatment for severe hypertensive intracerebral hemorrhage （SHIH）. Methods Between May 1997 and December 2003 A total of 110 cases of SHIH were divided into two groups with 55 cases in each group： Conservative Group （Control Group） was treated by medical conservative management, and Minimally Invasive Group was given a combination therapy of minimally invasive puncture and drainage, infusion with urokinase, and intravenous dripping of β -aescine sodium. Results In the Minimally Invasive Group, the rate of significant improvement, the total effective rate, and the death rate were 81.8% （45/55） , 89. 1% （49/55） , and 10.9% （6/55） , respectively. The corresponding values in the Control Group were 32.7% （18/55） , 49. 1% （27/55）, and 43.6% （24/55） , respectively. The curative effect in the Minimally Invasive Group was superior to that in the Control Group （X^2 = 20. 604, P = 0. 000）. Conclusions The combination therapy of minimally invasive puncture and drainage, infusion with urokinase, and intravenous administration of β - aescine sodium in the treatment of severe hypertensive intracerebral hemorrhage is simple, safe, and effective. The treatment has fewer complications and significantly improves the prognosis of patients.

关 键 词：重型高血压性脑出血 微创穿刺术 Β-七叶皂甙 尿激酶 

分 类 号：R651.12[医药卫生—外科学]