动脉粥样硬化血管重塑的认识与研究进展  

Atherosclerotic Arterial Remodeling

作　　者：黄广勇[1] 卢才义[1] 

机构地区：[1]中国人民解放军总医院老年心血管病研究所,北京100853

出　　处：《心血管病学进展》2005年第6期589-592,共4页Advances in Cardiovascular Diseases

摘　　要：血管重塑是影响动脉粥样硬化及球囊损伤后血管管腔面积的主要决定因素,血管重塑是在血流动力学、内皮功能及炎症等多因素参与下进行的,涉及到细胞的生长、凋亡、迁移及细胞外基质的合成、降解和重新排布,正性重塑比负性重塑伴随更明显的炎症和斑块易损性,而球囊损伤后的血管重塑以负性收缩性重塑为特征。Arterial remodeling is the major determinant of artery luminal area after atherosclerosis or balloon dilation. The process of arterial remodeling may involve hemodynamic, endothelial function and inflammation, which relate to growth, apoptosis, shift of cell as well as breakdown,build up and rearrange of extracellular matrix. Positive remodeling is associated with more inflammation response and vulnerable plaque. While balloon injury artery is characterized by negative remodeling.

关 键 词：动脉粥样硬化 血管重塑 

分 类 号：R543.5[医药卫生—心血管疾病]