固体酸催化剂合成2-乙酰噻吩  

The Synthesis of 2-Acetylthiophene with the Presence of Solid-acid Catalyst

作　　者：刘荣杏[1] 佘红梅[1] 张洪林[1] 张连红[1] 蒋林时[1] 

机构地区：[1]辽宁石油化工大学环境工程系,辽宁抚顺113001

出　　处：《当代化工》2005年第5期321-323,共3页Contemporary Chemical Industry

摘　　要：针对传统的合成2-乙酰噻吩的方法存在的一些弊端,选用环境友好型催化剂-磷钨酸来合成2-乙酰噻吩。磷钨酸除了具备一般质子酸的特点外,还具备一系列的优点:成本低、分解温度高、合成简便等。通过实验,考察了反应温度、反应时间和催化剂用量对该反应的影响,确定该反应的最适宜反应条件为:反应温度为85℃,反应时间为2.5 h,催化剂用量为0.5 g,产品的转化率约90%。产物通过色-质联用仪分析可知:产品2-乙酰噻吩质量分数约97.99%,副产物主要是少量的3-乙酰噻吩。由此也证明了磷钨酸作为本反应的催化剂,有着较高的选择性。这种方法同以往的方法相比较,更具备无设备腐蚀、减少环境污染等优势,产品同催化剂易于分离。The traditional preparing method of 2 - acetylthiophene has some disadvantages. So environmentally friendly solid- acid catalyst may be considered. Phosphotungsic acid has characteristic of hydroxy acid and some advantages： the cost is small, the preparation is simple, so it is feasible. By experiment, the effect of reaction time, reaction temperature and the amount of catalyst are studied, Preferred reaction conditions are determined： the suitable reaction temperature, reaction time and the amount of catalyst are 85℃, 2.5 h and 0.5 g. The convertion is high, about 90 %. By the analysis of GS and MS, the selectivity for 2 - acetylthiophene is 97.99 %.

关 键 词：磷钨酸 噻吩 2-乙酰噻吩 中间体 

分 类 号：TQ251.2[化学工程—有机化工]