消毒剂对乙型肝炎病人血液污染物品消毒的研究  

STUDY ON DISINFECTION OF ARTICLES CONTAMINATED BY BLOOD OF HEPATITIS B PATIENT WITH SPE DISINFECTANT

作　　者：涂瀛 熊鸿燕[1] 宋建勇[1] 李文全[1] 

机构地区：[1]第三军医大学流行病学教研室

出　　处：《中国消毒学杂志》1996年第1期12-18,共7页Chinese Journal of Disinfection

摘　　要：ＳＰＥ消毒剂主要杀菌成分为过氧戊二酸。经测试，将配成含２．０％过氧戊二酸的ＳＰＥ消毒液溶液，于４０℃作用６０分钟，可将乙型肝炎病人血液污染物品上的ＨＢｓＡｇ完全破坏。该消毒剂毒性低，腐蚀性小。The SPE disinfectant is a compound disinfectant containing perglutaric acid as the main germicidal component. The results of disinfection test at 40℃ indicated that the SPE disinfectant solution containing 1 2% perglutaric acid with a 40-minute contact time could destroy over 99.9% of HBsAg in blood and the solution containing 2.0% perglutaric acid with a 60-minute contact time could completely destroy HBsAg on the articles contaminated by the blood of hepatitis B patient. The toxicity test indicated that the acute oral LD 50 of SPE disinfectant in mice was 3 265 mg/kg. The disinfectant was not irritative to skin and slightly irritative to conjunctiva and iris. Material destruction test indicated that the SPE disinfectant solution containing 2.0% perglutaric acid had no significant influence on breaking strength of cotton cloth and latex tube and only caused decrease in color. It was not apparently corrosive to stainless steel, slightly corroded copper and aluminum, and corroded carbon steel rather heavily. During storage of SPE disinfectant powder at 4～10℃, the perglutaric acid content decreased by about 4% every month in average.

关 键 词：过氧戊二酸 乙型肝炎病毒 灭活 SPE消毒液 

分 类 号：R187.1[医药卫生—流行病学] R373.2[医药卫生—公共卫生与预防医学]