异佛尔酮芳构化合成3,5-二甲基苯酚研究进展  

Development of Aromatization of Isophorone to 3,5-Xylenol

作　　者：张宪[1] 王日杰[1] 于金刚[1] 孔海宁[1] 田桂林[2] 

机构地区：[1]天津大学化工学院,天津300072 [2]天大天久科技股份有限公司,天津300072

出　　处：《化学工业与工程》2005年第6期472-475,共4页Chemical Industry and Engineering

摘　　要：3,5-二甲基苯酚是一种重要的医药中间体。国内目前生产工艺是间二甲苯的磺化碱熔法,该方法工艺过程复杂、污染严重,并且产品纯度不高。与传统工艺相比,异佛尔酮的催化芳构化制备3,5-二甲基苯酚方法具有很多优点。本文对两种工艺路线进行了比较,论述了异佛尔酮催化芳构化的研究进展。3,5-xylenol is an important medical intermediate. Recent method of synthesizing 3,5-xylenol is sulpho alkaline fusion of dimethylbenzene, it is a very complicated procedure with serious pollution and lowpure products. Co many advantages. mpared with traditional way, catalytic aromatization of isophorone has been proved to have Furthermore, two synthesising routes are compared and the research of catalytic aromatization of isophorone is summarized in this paper.

关 键 词：3 5-二甲基苯酚 异佛尔酮 芳构化 

分 类 号：O624.422[理学—有机化学] TQ332.47[理学—化学]