舒经汤治疗痛经及对患者血液流变学的影响  

Clinical Study of Shujingtang in Treating Dysmenorrhea and Effect on Hemorheology

作　　者：周家茂[1] 易吉冬 郭富桃 李葵香[1] 周小兵[1] 

机构地区：[1]湖南环境生物学院医学部,湖南衡阳421001 [2]衡阳市中医院,湖南衡阳421001 [3]衡阳市第五医院,湖南衡阳421002

出　　处：《中国中医药信息杂志》2005年第11期15-17,共3页Chinese Journal of Information on Traditional Chinese Medicine

摘　　要：目的探讨舒经汤治疗原发性痛经的疗效及安全性。方法将62例原发性痛经患者随机分为3组,其中治疗组21例(口服舒经汤)、中药对照组21例(口服痛经宝颗粒)、西药对照组20例(口服双氯芬酸),观察各组的临床疗效、血液流变学变化及不良反应。结果治疗组、中药对照组及西药对照组的总有效率分别为95.2%、90.5%及77.8%。治疗前治疗组的血浆粘度(1.60±0.23)mPa·s,纤维蛋白原(4.40±1.18)g/L,均值略高于健康组,其中血沉均值与健康组比有非常显著差异(P<0.01)。而治疗后血浆粘度(1.34±0.18)mPa·s,纤维蛋白原(3.32±1.27)g/L,均值与健康组比无差异,其中血沉与健康组比较无显著性差异(P>0.05)。治疗组和中药对照组均未见明显不良反应,西药对照组主要表现为消化道反应。结论舒经汤治疗原发性痛经疗效确定,且远期疗效及安全性均优于西药对照组。Objective To investigate the efficacy and safety of Shujingtang （SJT） in treating dysmenorrhea.Methods 62 cases of dysmenorrhea were divided into three groups, 21 cases of treatment group （took SJT}, 21 cases of TCM control group （took Tongjingbao） and 20 cases of the western medical control group （took Diclofenac sodium）. The clinical therapeutic effectiveness, effect of hemorheology and reaction of poisonous side effect were observed in three groups. Results The total effective rate of the three groups （the treatment group, the TCM control group and the western medical group） was 95.2%, 90.5% and 77.8% repectively. Before treatment, the average levels of plasma viscosity （1.60±0.23 mpa.s） and fibrinogen （4.40±1.18 g/L） of treatment group were higer than the levels of health group, while the average level of ESR of treatment group was much higher than the level of health group （P〈0.01）. After treatment, the levels of plasma viscosity （1.34±0.18 mpa.s） and fibrinoen （3.32±1.27 g/L） were no difference between the treatment group and the health group, while the level of ESR was no significant statistical difference between the treatment group and the health group （P〉0.05）. Patients of treatment group and TCM group had no obvious poisonous side effect showed, but reaction of digestive system showed in the western medical group. Conclusion Not only Shujingtang had certain therapeutic effectiveness in treating dysmenorrhea, but also the therapeutic effectiveness at distant period and the safety were better than the western medical group.

关 键 词：原发性痛经 舒经汤 临床研究 

分 类 号：R271.113[医药卫生—中医妇科学]