未分类湿疹患者血清白细胞介素12水平研究  

The IL-12 level in the sera of patients with unclassified eczema

作　　者：尤艳明[1] 李林峰[1] 

机构地区：[1]北京大学第三医院皮肤科,100083

出　　处：《中国麻风皮肤病杂志》2005年第11期864-865,共2页China Journal of Leprosy and Skin Diseases

摘　　要：目的:研究未分类湿疹患者血清IL-12水平。方法:应用ELISA方法测定了65例未分类湿疹患者血清白细胞介素12(IL-12)水平并与30例无过敏史健康对照者进行了比较。结果:(1)未分类湿疹患者血清IL-12水平高于对照组(P=0.04)。(2)急性期未分类湿疹患者血清IL-12水平和对照组相比无显著差异。(3)慢性期未分类湿疹患者血清IL-12水平高于对照组(P=0.004)。(4)急性期未分类湿疹患者血清IL-12水平和慢性期相比无显著差异。结论:在未分类湿疹的发病机制中,IL-12可能起一定的作用。Objective： To investigate the role of IL- 12 in the pathogenesis of unclassified eczema （UE）. Methods： The level of serum IL- 12 in 65 patients with UE was detected by ELISA and compared with health controls. Results： （1） The level of serum IL- 12 in UE was higher than that of control （ P =0.04） ; （2） The level of serum IL- 12 in acute UE was not different with that of control. （3） The level of serum IL- 12 in chronic UE was higher than that of control （ P = 0.004）. （4） The level of serum IL - 12 in acute UE was not different with that of chronic UE. Conclusion： The results indicate that IL- 12 may play an important role in UE.

关 键 词：IL-12 未分类湿疹 血清白细胞介素 未分类 白细胞介素12 湿疹 患者 水 ELISA方法 对照组 

分 类 号：R758.23[医药卫生—皮肤病学与性病学]