早婴儿特应性皮炎发病因素探讨  

The Evaluations on some factors in the pathogenesis of childhood AD

作　　者：陈海霞[1] 苑芳昌[1] 

机构地区：[1]日照市人民医院皮肤科,山东日照276826

出　　处：《食品与药品》2005年第11A期55-56,共2页Food and Drug

摘　　要：目的观察纯母乳喂养特应性皮炎(atopic dermatitis,AD)患儿皮损处金黄色葡萄球菌(金葡菌)带菌率,与黄疸的相关性及乳母饮食对AD的影响,探讨上述因素在AD发病中的作用。方法由AD皮损局部、非皮损局部分离金葡菌,经皮测定黄疸指数,将乳母饮食随机分组,并与对照组进行统计学比较。结果与对照组相比,AD患儿皮损局部金葡菌比对照组升高明显,黄疸与AD的发病无统计学意义,乳母饮食与AD有关。结论AD患儿皮损区带菌率45%,黄疸与AD的发病无相关性,乳母饮食情况参与AD发病。Objectives To observe the prevalence of Staphylococcus aureus（S.aureus） colonization in lesions of breast feeding childhood atopic dermatitis（AD）,the correlation between the jaundice and AD ,as well as the impact on AD of the mothers iet ,and evaluate the roles of these factors in the pathogenesis of childhood AD. Methods Specimens were taken from the skin lesions of 60 patients, non-lesional skin of 30 patients and the skin of 30 controls for bacterial cultures.Determine icterus index through the skin and divide the mothers freely into two groups.One group（A） stopped eating fish,eggs,milk ect, and the other group（B） ate as they did before. Results The prevalence of S.aureus colonization was significantly increased in the lesional skin of patients with AD in comparison with the controls（P〈0.05）.There was no significant differnce in AD between the patients with and without jaundice（P〈0.05）. Conclusions S.aureus can be isolated from 45% of AD lesions.There is no correlation between the AD and jaundice. But mothers＇ diet can influences on the pathogenesis of childhood AD.

关 键 词：特应性皮炎 金黄色葡萄球菌 黄痘 乳母膳食 婴儿 

分 类 号：R729[医药卫生—儿科]