康健钠降糖作用机理的初步研究  

A Preliminary Study of Mechanism on Lower Glucose of Kangjianna

作　　者：石明健[1] 刘惟莞[1] 王红英[1] 

机构地区：[1]湖北医科大学药理学教研室,武汉430071

出　　处：《湖北医科大学学报》1996年第1期17-28,共12页

摘　　要：旋光测定法对康健钠降糖机理进行初步研究表明：康健钠瑟葡萄糖溶液作用后，其旋光度下降０．４°，即浓度降低２５％，故康健钠对葡萄糖分子有部分结合作用。在体大鼠粪便含糖量测定表明，康健钠增加大鼠粪便含糖量。提示由于康健钠的结合使用，妨碍了葡萄糖在胃肠道的吸收，增加其排泄。这可能是其降糖机理这一。The mechanism on lower glucose of Kangjianna was studied initially.The result showed that Kangjianna lowered the optical rotation of glucose solution of 0.4°,namely,the concentra- tion of glucose solution decreased by 25%,when it was mingled into glucose solution.It was demonstrated that Kangjianna could combine with glucose partly.It increased contents of glu- cose in rat's feces compared with the control group (P<0.01).The result indicated that Kangjianna decrease absorbtion of glucose in gastrointestinal tract because of absorbing glucose.

关 键 词：降血糖药 药理学 康健钠 

分 类 号：R977.15[医药卫生—药品]