葡萄球菌感染的耐药性监测和治疗对策  

Study on Antimicrobial Resistance and Therapeutic Strategy on Staphylococcus Infections

作　　者：邓健康[1] 霍亚平[1] 郭晓兰[1] 

机构地区：[1]川北医学院附属医院检验科,四川南充637000

出　　处：《中国误诊学杂志》2005年第14期2615-2616,共2页Chinese Journal of Misdiagnostics

摘　　要：目的:了解葡萄球菌的耐药情况,指导临床合理使用抗生素。方法:用VITEK-32、GPI、GPS-107进行菌种鉴定、耐甲氧西林葡萄球菌(MRS)检测和药敏实验。结果:188株葡萄球菌中凝固酶阴性葡萄球菌(CNS)136株,其中耐甲氧西林凝固酶阴性葡萄球菌(MRCNS)120株,检出率为88.2%。MRS对万古霉素、呋喃妥因100%敏感,对利福平敏感性高。结论:我院MRS检出率较高,应重视对MRS耐药性的监测,治疗由MRS菌株引起的严重感染应首选万古霉素。Objective：To survey the resistance of Staphylococcus,and to provide the reference for the clinical antimicrobial agents usage. Methods：The identification and drug susceptibility tests were carried out with Vitek-32,GPI and GPS-107 for Staphylococcus. Results：Among 188 strains of staphylococcus ,136 trains wereresistant coagulase negative staphylococcu.s （CNS）,of which 120 were methicillin coagulase negative staphylococcus （MRS）with thedetectiong rate of 88, 2%. MRS was susceptible to vancomycin, nitrofurantoin and rifampin, Conclusions：We should pay much attention to detecting MRS, the resistance of MRS to antibiotics should be further monitored. Vancomycin may be used for the treatment of MRS infection first.

关 键 词：葡萄球菌属/药物作用 抗药性 细菌 菌药/治疗应用 葡萄球菌感染/药物疗法 

分 类 号：R378.11[医药卫生—病原生物学]