实时三维超声心动图估测左室质量的实验研究  

Experi mental study of real-time three-dimensional echocardiography for quantitative analysis of left ventricular mass

作　　者：陈国珍[1] 孙锟[1] 陈树宝[1] 张玉奇[1] 洪雯静[1] 薛海虹[1] 

机构地区：[1]上海第二医科大学附属新华医院上海儿童医学中心心内科,上海200127

出　　处：《临床儿科杂志》2005年第8期577-580,共4页Journal of Clinical Pediatrics

基　　金：国家自然科学基金资助项目(编号:30371497);教育部优秀青年教师资助计划(编号:2002350)

摘　　要：目的探讨实时三维超声心动图(3DE)估测左室质量的可行性和准确性。方法应用Philips实时3DE采集19只离体猪心金字塔形数据库,结合相应测量软件用心尖长轴系列平面法分别测量左室壁质量,并与二维超声(2DE)双平面Simpson法和离体猪心排水法实测值比较。结果实时3DE16平面法(201.92±26.43)g、8平面法(201.84±27.60)g估测左室壁质量值与猪心排水法实测值(206.79±26.74)g无统计学差异(P>0.05),而2平面法(167.74±22.15)g和2DE双平面Simpson法(183.54±24.54)g测值与排水法实测值有统计学差异(P<0.05);实时3DE16平面(r=0.92,P=0.0001)和8平面法测值(r=0.91,P=0.0001)与排水法实测值高度相关,2DE双平面Simpson法则较逊(r=0.74,P=0.0001)。结论实时3DE是估测左室壁质量的可靠手段。Objective To evaluate the feasibility and accuracy of real-time three-dimensional echocardiography（3DE）for quantitative analysis of left ventricular mass. Methods Nineteen excised porcinehearts were examined by real-time 3DE and conventional two-dimensional ecnocardiograpny （2DE） With Philips Sonos 7500 echocardiographic system. Left ventricular wall mass examined by real-time 3DE was outlined and calculated with 2-plane, 4-plane, 8-plane and 16-plane method using the 4D Cardio-View RT of Tom Tec image system, and the results were compared with those examined by 2D biplane Simpson-method. The true value of left ventricular wall mass measured by water displacement served as a reference standard. Results “Full volume” imaging in all excised porcine hearts was well displayed by real-time 3DE. There was no significant difference （P 〉 0.05） between the values of left ventricular wall mass examined by real-time 3DE 16-plane （201.92）± 26.43）g,8-plane（201.84±27.60） g and that by water displacement （206.79 ±26.74） g, but there was significant difference（P〈0.05） between the values by real-time 3DE 2-plane（167.74±22.15） g, 2D biplane Simpson-method （183.54± 24.54） g and that by water displacement. Meanwhile, the values of left ventricular wall mass measured by RT-3DE 16-plane（r = 0.92, P =0.0001）and 8-plane（ r = 0.91,P = 0. 0001）were highly correlated with that by water displacement. The correlation between 2DE biplane Simpson-method and water displacement（ r = 0.74） was less significant for left ventricular wall mass measurement than that between 3DE 16-plane, 8-plane and water displacement. Conclusions Real-time 3DE may be a valuable and accurate technique for quantitative analysis of left ventricular wall mass.

关 键 词：实时 三维超声心动描记术 左室壁质量 

分 类 号：R445.1[医药卫生—影像医学与核医学]