多动安口服液的提取工艺  

Study on extraction of Duodongan oral solution

作　　者：谈瑄忠[1] 

机构地区：[1]南京市中医院,江苏南京210001

出　　处：《中国医院药学杂志》2005年第5期398-400,共3页Chinese Journal of Hospital Pharmacy

基　　金：江苏省科技厅立项资助课题(编号:BS98073)

摘　　要：目的正交优选多动安口服液提取工艺。方法采用L9(3)4正交试验法,以阿魏酸、甘草酸及提取物为指标分别进行醇提、水提工艺优化选择,考察各因素的影响。结果醇提最佳工艺为每次6倍量60%乙醇回流提取3次,每次1.5h为最佳。水提最佳工艺为以药材浸泡1.5h后每次用10倍量水,煎煮提取3次,每次1.5h为最佳。结论优选的制备工艺有效成分含量高,工艺稳定可行。OBJECTIVE To study the optimum extraction process of Duodongan oral solution. METHODS The optimum extrac- tion conditions were studied by the orthogonal test in ferulic acid,and glycyrrhizic acid as markers. RESULTS The optimum extraction process condition obtained was adding 6-fold of alcohol which concentration was 60%, decocting three times 1.5 hours and was adding 10-fold of water,decocting three times 1.5 hours each time. CONCLUSION The optimized process is stable and feasible and result in high content of active constituent.

关 键 词：多动安口服液 提取工艺 当归 

分 类 号：R238.16[医药卫生—中医学]