常德市3 803名高考生乙型肝炎病毒血清学标志物检测  

Analysis of HBV Infection Serological Markers in Graduating Students of Senior School

作　　者：廖可育[1] 熊昌本[1] 史开垠[1] 彭志高[1] 侯宏锦[1] 罗玲[1] 肖潇[1] 刘小林[1] 熊玉珍[1] 白熠[1] 

机构地区：[1]湖南省常德职业技术学院,湖南常德415000

出　　处：《实用预防医学》2005年第5期1108-1109,共2页Practical Preventive Medicine

摘　　要：目的了解常德市高考生乙型肝炎病毒(HBV)感染情况。方法对2003年3803名高考生采用酶联免疫法(ELISA)检测乙型肝炎病毒标志物(HBVM),赖氏法测定丙氨酸氨基转移酶(ALT)。结果常德市高考生的HBVM阳性率为28.08%,市区、乡镇高考生HBVM阳性检出率分别为27.21%、34.29%,乡镇明显高于市区(P<0.01),无性别差异。HBVM有19种组合模式,HBsAg阳性率为4.60%,其中市区为4.47%、乡镇为5.36%,市区与乡镇无明显区别(P>0.01);单纯HBsAb占总检人数16.83%。HBVM阳性学生与HBVM阴性学生ALT异常率分别为0.79%、0.07%,两者之间差异有显著性(P<0.01)。结论乙肝防治工作中,注意HBsAg阳性感染者时不要忽视HBsAg阴性的HBV感染者,同时要注意对HBV感染者的肝功能保护。对HBV易感者应及时接种乙型肝炎疫苗。Objective To understand the condition of hepatitis B infection among graduating students of senior school in Changde. Methods ALT levels were measured, and serological markers of hepatitis B virus infection were detected by ELASA among graduating students of senior school in Ohangde in 2003. Results The positive rate of the students HBVM was 28.08 %, without significant sex difference （P〉0.01）. The urban students positive rate was 27.01% and the rural students was 34.29 % （ P〈 0.01 ）. The positive rate of HBsAg, however, was 4.60 %, without significant district difference （ P 〉 0.01）. The students with only HBsAb- positive accounted for 16.83%. The abnormal rate of ALT was 0.79% among the cases with positive HBVM, abnormal rate of ALT was 0.0＂7 % among the cases with negative HBVM （ P〈 0.01 ）. Conclusion In an attempt to control HBV infection, not only the HBsAg HBeAg positive, but also the HBsAgHBeAg negative students should not neglect also, and have their liver function test monitored regularly. Preventive vaccination should be strengthened.

关 键 词：学生 HBV感染 体检 

分 类 号：R373.2[医药卫生—病原生物学]