电针不同穴位对单眼视神经离断家兔FVEP的影响  

Effects of electroacupuncture at different acupoints on FVEP in the rabbit with separated monocular optic nerve

作　　者：周华祥[1] 刘文舟[2] 段俊国[1] 江文珊[3] 陈晓莉[4] 

机构地区：[1]成都中医药大学眼科实验室,四川610075 [2]银川市解放军第五医院眼科 [3]第三军医大学西南医院眼科 [4]成都中医药大学针灸教研室

出　　处：《中国针灸》2005年第10期725-728,共4页Chinese Acupuncture & Moxibustion

基　　金：国家自然科学基金资助项目:39470866

摘　　要：目的探讨针灸影响视觉系统的效应及其机理,明确视神经中之离中纤维在针刺影响视觉功能过程中的作用。方法24只白兔随机分为“合谷”组与“太溪”组,每组12只,制作单眼视神经离断家兔模型,切断视网膜与中枢的联系,但不损伤视网膜血循环,观察电针对双眼闪光视觉诱发电位(FVEP)的影响。结果在切断视神经时下行调制视网膜的离中纤维也被切断,术眼FVEP熄灭。电针“合谷”与“太溪”穴各时期对FVEP之N1、P1、N2各波峰潜时、振幅均有较强的抑制作用,表现为峰潜时延长,振幅明显降低,且这种抑制作用具有穴位的差异性。结论离中纤维在电针影响家兔闪光视网膜电图(FERG)及FVEP的过程中起到一定的作用,但针刺对FERG影响的主要途径不是通过中枢的下行性抑制,而是通过影响离中纤维在有限程度上对视网膜产生的影响。Objective To study the effect of acupuncture and moxibustion on the visual system and the mechanism. Methods Twenty-four rabbits were randomly divided into a “Hegu”（LI 4） group and a “Taixi” （KI 3） group, 12 rabbits in each group. The rabbit model with separated monocular optic nerve was developed, cutting the link between the retina with the center, but do not injure the blood circulation in the retina. The effect of electroacupuncture on flicker vision evoked potential （FVEP） was investigated. Results When the optic nerve was cut off, the distal fibers of descending regulating the retina were cut off, the FVEP of the operative eye extinguished. Electroacupuncture at “Hegu”（LI 4） and “Taixi”（KI 3） at various stages have stronger inhibiting action on the latent time and amplitudes of N1, P1, N2 of FVEP, marked by prolongation of the latent time of peak, and obvious decrease of the amplitude. And this inhibiting action has difference of acupoints. Conclusion The distal fiber plays a certain role in the process of electroacupuncture influencing flicker electroretinogram （FERG） and FVEP, but the effect of acupuncture on FERG is induced through the distal fibers to influence the retina in a limited extent, but not through the central descending inhibition.

关 键 词：电针 视网膜/损伤 诱发电位 视觉/针灸效应 兔 

分 类 号：R246.82[医药卫生—针灸推拿学]