CK,CK-MB与Hs-CRP联合应用在心血管疾病诊断中的价值  

The value of CK, CKMB and Hs-CRP in Diagnosis of Cardiovascular Diseases

作　　者：胡敏[1] 廖可宏[1] 陈新瑞[1] 秦立新[1] 

机构地区：[1]中南大学湘雅二医院检验科,湖南长沙410011

出　　处：《实用预防医学》2005年第3期498-500,共3页Practical Preventive Medicine

摘　　要：目的观察超敏C-反应蛋白与CK、CK-MB在心血管疾病中的变化情况,评价在心血管疾病诊断中的应用价值。方法测定44例急性心梗,42例不稳定型心绞痛,21例稳定型心绞痛患者血浆CK、CK-MB、Hs-CRP浓度,并进行统计学分析。结果Hs-CRP,CK在AMI升高最明显,不稳定型心绞痛次之;CK-MB在AMI升高最明显,而稳定型心绞痛及不稳定型心绞痛两组间比较无显著性差异,但较对照组有显著升高。结论Hs-CRP、CK、CK-MB显著升高可辅助临床诊断急性心梗,而对稳定型心绞痛及不稳定型心绞痛的鉴别诊断无明显的诊断价值。Objective To observe the changes of serum levels of OK, OK - MB and Hs- ORP in patients with cardio- vascular diseases. Methods Serum levels of OK, OK - MB and Hs - ORP were detected in 44 patients with acute myocardial infarction （AMI）, 42 patients with unstable angina pectoris （UAP） and 21 patients with stable angina pectoris （SAP）. Results Serum levels of CK, OK - MB and Hs - ORP increased significantly in AMI group than in UAP group, OK - MB in both UAP and SAP groups was higher than control group, but not had the power to show statistical significant difference between them. Conclusions The obviously increased OK, OK - MB and Hs - ORP are useful in the diagnosis of AMI, but unable to distinguish between UAP and SAP.

关 键 词：肌酸激酶 肌酸激酶同工酶类 超敏C-反应蛋白 心血管疾病 

分 类 号：R54[医药卫生—心血管疾病]