注射用头孢拉定助溶剂低松密度精氨酸的结晶工艺  

Crystallization process of low bulk-density L-arginine as cosolvent for cefradine for injection

作　　者：梁宝臣[1] 陈慧[1] 董迎[1] 

机构地区：[1]天津理工大学生物与化学工程学院,天津300191

出　　处：《中国抗生素杂志》2005年第11期693-694,共2页Chinese Journal of Antibiotics

摘　　要：采用溶析结晶法,通过优化结晶工艺条件,制备出松密度在0.25～0.40g/cm3的精氨酸结晶,提高其与头孢拉定原粉的混合、分装均匀性.The L-arginine crystals about 0.25-0.40 g/cm^3 of bulk-density have been prepared by the methods of solvent-out crystallization in optimized condition, and the uniformity of the mixing cefradine and L-arginine was improved.

关 键 词：精氨酸 头孢拉定 结晶 松密度 混合 

分 类 号：TQ465[化学工程—制药化工]