生理盐水漱口预防急性白血病化疗后真菌性口腔炎的研究  

A study on effect of normal saline gargling to prevent mycotic stomatitis of acute leukemia patients after chemotherapy

作　　者：赵凤军[1] 王银萍 赵秀荣 杨丽红[1] 王玉华[1] 

机构地区：[1]山东省聊城市人民医院,252000 [2]山东省聊城市计划生育委员会,252000 [3]山东省聊城市东昌府区人民医院,252000

出　　处：《护理研究（中旬版）》2005年第11期2370-2371,共2页Chinese Nursing Researsh

摘　　要：[目的]探讨生理盐水漱口对急性白血病化疗后真菌性口腔炎的预防作用。[方法]将120例首诊急性白血病病人随机分成对照组和实验组,对照组采用2.5%碳酸氢钠液漱口,实验组采用生理盐水漱口,急性非淋巴细胞性白血病病人漱口从化疗第1天开始至化疗结束后21d,急性淋巴细胞性白血病病人从化疗第1天开始,连续漱口28d,于每天晨、晚及3餐后漱口,比较两种漱口液预防真菌性口腔炎的效果。[结果]实验组霉菌性口腔炎发生率低于对照组(P<0.05)。[结论]生理盐水漱口可预防急性白血病化疗后真菌性口腔炎。Objective： To probe into the preventative effect of sodium chloride gargling on mycotic stomatitis of acute leukemia patients induced by chemotherapy. Method： A total of 120 primarily diagnosed acute leukemia patients were divided into test and control group randomly, Patients of test group were gargled with nor- mal saline during chemotherapy, while the patients of control group were gargled with 2.5 % sodium bicarbonate. The gargling times were five times per day including morning, night and three times after meals for the acute non - lymphoblastic leukemia （ANLL） patients started from the first day to the 21st day during whole chemotherapy and for the acute lymphoblastic leukemia （ALL） patients began with the first day of treatment for 28 days continuously respectively. The prevention effect from mycotic stomatitis of all two groups cases by gargling with the two kinds of medical liquids were observed, Result： The incidence of myocotic stomatitis of test group is lower than that of control （P 〈 0.05）. Conclusion： Gargling with normal saline have an effect on preventing the myocotic stomatitis for acute leukemia patients after undergoing chemotherapy.

关 键 词：急性白血病 生理盐水 碳酸氢钠 真菌性口腔炎 

分 类 号：R473.5[医药卫生—护理学]