应用导管介入技术治疗子宫肌瘤和宫颈癌  

Catheter Intervention for Hysteromyoma and Cervical Cancer

作　　者：张学军[1] 马和平[1] 甄彦利[1] 朝鲁孟[1] 梁秀琴[1] 周群慧[1] 顾苏滨[1] 王虹[1] 刘鹏芝[1] 

机构地区：[1]内蒙古自治区医院介入科,内蒙古呼和浩特010017

出　　处：《内蒙古医学杂志》2005年第11期983-986,共4页Inner Mongolia Medical Journal

摘　　要：目的:分析评价应用导管介入技术治疗子宫肌瘤和宫颈癌的临床疗效.方法:选择19例子宫肌瘤、13例宫颈癌皆经一侧股动脉入路,行两侧子宫动脉插管,对肌瘤者分别选择KMG、PVA微球或碘化油+平阳霉素乳剂,栓塞阻断其血供;宫颈癌者应用明胶海绵颗粒+抗癌药物行手术前灌注栓塞辅助治疗.结果:19例子宫肌瘤、13例宫颈癌共64支子宫动脉均插管成功并栓塞,同时对宫颈癌行双侧髂内动脉和子宫动脉抗癌药物灌注,19例子宫肌瘤经3～12个月随访,平均瘤体缩小率59.4%,多发者中的部分小肌瘤消失,1例坏死脱落,临床症状明显改善;13例宫颈癌介入治疗3周后手术切除顺利,标本组织学示癌巢趋向消失,周边组织有淋巴细胞浸润,部分宫颈恢复正常,其中2例癌组织消失,本组32例介入治疗后皆无严重并发症发生.结论:介入治疗子宫肌瘤安全、微创且疗效肯定;对宫颈癌术前介入可有效提高手术切除率和降低复发率,值得临床广泛应用.Objective：To analyze and evaluate the clinical efficacy of catheter intervention in treating hysteromyoma and cervical cancer. Methods：19 cases of hysteromyoma and 13 cases of cervical cancer were selected and applyed bilateral uterine arterial intubation, with KMG,PVA particles or lipiodol - PYM emulsion in hyste- romyoma and gelatin spongia granula combined with anticancer drugs in cervical cancer. Results ： The intulation and embolism in total 64 uterine arteries was successful,and anticancer drugs were infused in bilateral internal iliac arteries and uterine arteries in cervical cancer. Followed up 3 months to 12 months, the average diminished rate of hysteromyoma was 59.4%. Some small tumors disappeared in cases with multiple hysteromyoma and shedded in 1 case. Clinical symptoms obviously improved. The operation in 13 cases of cervical cancer performed successfully at 3 weeks after interventional therapy. Their histological specimens showed disappearing cancer tissue, with peripheral infiltrating lymphocytes. The cervix in some cases recovered to normal including 2 cases with disappedred cancer tissue. There was no serious complications in all 32 cases after interventional therapy. Conclusion：The interventional therapy for hysteromyoma is safe, minitrauma and effective. Preoperative interventional therapy for cervical cancer can effectively improve the rate of surgical excision and decrease recurrence rate. It should be recommended.

关 键 词：子宫肌瘤 宫颈癌 介入治疗 

分 类 号：R851[医药卫生—航空、航天与航海医学] R737.33[医药卫生—临床医学]