哮喘儿童诱导痰液安全性分析  

Safety analysis of sputum induction in children with asthma

作　　者：罗征秀[1] 蒋永惠[1] 龚财惠[1] 刘恩梅[1] 符州[1] 

机构地区：[1]重庆医科大学附属儿童医院呼吸科,重庆400014

出　　处：《重庆医科大学学报》2005年第5期755-756,762,共3页Journal of Chongqing Medical University

基　　金：国家自然科学基金资助(基金号30470760)

摘　　要：目的:探讨高渗盐水诱导哮喘儿童痰液的安全性。方法:52例哮喘儿童(急性发作期37例,缓解期15例)及10例正常健康儿童进行高渗盐水痰液诱导,测定诱导前、诱导后20min最大呼气流量(PEF)、第1秒用力呼气容积(FEV1)、心率(HR)、呼吸频率(RR)的变化,观察患儿出现的不适反应。结果:各组儿童诱导前后PEF、FEV1、HR、RR值无显著性变化(P>0.05),不适反应发生率低,仅为6.5%。结论:对哮喘儿童进行高渗盐水痰液诱导是一种安全的方法。Objective：To investigate the safety of hypertonic saline induced sputum in asthmatic children. Methods：52 asthmatic children（including 37 cases of exacerbation, 15 cases of remission） and 10 normal children were selected to induce sputum by hypertonic .saline and pre or post sputum induction the peak expiratory flow（PEF） , forced expiratory volume in one second（ FEV1 ）, heart rate（HR）, respiratory rate（ RR ） were detected. Results ： No significant difference in PEF, FEV1, HR and RR values after sputum in- duction was found between two groups（ P 〉0.05）. Cnclusion：Hypertonic .saline sputum induction is a safe technique for asthmatic children.

关 键 词：哮喘 痰诱导 高渗盐水 儿童 

分 类 号：R725.6[医药卫生—儿科]