切吸联合不同溶核疗法治疗腰椎间盘突出症  

Treatment of lumbar intervertebral disc herniation with percutaneous lumbar discectomy and different collagenase injections

作　　者：余庆阳 何斌[2] 

机构地区：[1]龙岩市博爱医院骨伤科,福建龙岩364000 [2]南京医科大学第二附属医院骨科

出　　处：《中国骨伤》2005年第10期593-596,共4页China Journal of Orthopaedics and Traumatology

摘　　要：目的分析比较3种不同联合疗法治疗突出型L4,5椎间盘突出症的临床疗效,并观察其不良反应。方法本组59例,男36例,女23例;年龄19～69岁,平均(38.18±10.24)岁。将所有病例随机分为3组进行相应治疗切吸+盘内法组(A组)15例,切吸+盘外法组(B组)26例,切吸+盘内外法组(C组)18例。结果59例术后进行了4个月以上的随访,近期总优良率72.88%,总有效率96.61%;远期总优良率72.88%,总有效率86.44%。但各组间近、远期疗效差异均无显著性意义(P>0.05)。结论以上3种不同联合疗法均是临床治疗突出型腰椎间盘突出的有效方法,且不良反应少。Objective： To compare and evaluate effects and adverse reaction of three different methods in the treatment of lumbar intervertebral disc herniation. Methods. Fifty-nine patients of lumbar intervertebral disc herniation, involving 36 cases of male and 23 cases of female with age from 19 to 69 （averagely 38.18 ± 10.24） years,were divided randomly into three groups：Group A in which patients were treated with percutaneous lumbar discectomy and intervertebral disc injection （15 cases） ;group B, treated with percntaneous lumbar discectomy and epidural injection （26 cases） ;group C, treated by percntaneous lumbar discectomy, intervertebral disc and epidural injection （18 cases）. Results：All the patients were followed up for more than 4 months. There were no significant difference in near-term and long-term clinical effects among the three different treatments. The total rates of excellent and good clinical effects were the same, i. e. 72.88 %, in the nearterm and the long-term evaluations. The total effective rate was 96.61% in the near-term evaluation, and 86.44% in the long-term evaluation. Conclusion： The three different methods are effective for lumbar disc herniation, of which adverse reaction is few.

关 键 词：椎间盘移位 椎间盘切除术 经皮 椎间盘化学溶解术 

分 类 号：R681.53[医药卫生—骨科学] R253[医药卫生—外科学]