甲状腺机能亢进患者^(131)I治疗后内分泌调节恢复过程的初步研究  

An Initial Study on Recovery Course of Endocrine Regulation in Hyperthyroidism after ^(131)I Therapy

作　　者：吕建莉[1] 戚良晨[2] 王雷[2] 赵学良[2] 

机构地区：[1]长春市第二医院,吉林长春130062 [2]吉林大学中日联谊医院

出　　处：《中国实验诊断学》2005年第5期696-697,共2页Chinese Journal of Laboratory Diagnosis

摘　　要：目的初步研究131I治疗后甲亢患者内分泌调节恢复的过程。方法选取本院核医学科1999年1月~2002年1月131I治疗后的甲亢患者,取3个月、6个月、9个月1、年、2年五个时间点共280例,进行随访。记录并分析血清T3(三碘甲状腺原氨酸)、T4(甲状腺激素)和hTSHu(高灵敏度促甲状腺素)浓度变化过程。结果随时间推移,随访患者T3、T4和TSH正常人数所占比例逐渐升高。结论T3、T4和hTSHu浓度变化能基本反映甲状腺的功能状态以及下丘脑-垂体-甲状腺轴功能的恢复情况。Objective To study the recovery course of pituitary-thyroid axis through a follow-up survey on hyperthyroidism patients after^131 I therapy. Methods Choose 280 patients who received^131 I therapy during 1999 - 2002 in department of Nuclear Medicine in our hospital, set five time spots to practice a follow-up survey by testing the patients＇ serum levels of T3/T4 and hTSHu. Then, analysis the data to search the recovery course. Results As time prolonged, the serum levels of T3/T4 and hTSHu gradually return to normal. Conclusion Serum T3/ T4 and hTSHu results can basieally reflect the state of thyroid and the recovery station of pituitary-thyroid axis for oafients received ^131 I Therapy.

关 键 词：甲亢^131I 内分泌 

分 类 号：R581.1[医药卫生—内分泌]