BiPAP呼吸机治疗急性呼吸衰竭疗效的早期预测指标探讨  

The early predictive indexes of curative effect of acute respiratory failure treated with noninvasive bilevel positive airway pressure ventilation

作　　者：杜娟[1] 邱晨[1] 高伟良[1] 付应云[1] 

机构地区：[1]暨南大学第二附属医院深圳市人民医院呼吸内科,广东深圳518020

出　　处：《中国医师杂志》2005年第11期1473-1475,共3页Journal of Chinese Physician

摘　　要：目的探讨B iPAP呼吸机治疗急性呼吸衰竭疗效的早期预测指标。方法68例急性呼衰患者使用B iPAP呼吸机治疗,根据治疗效果分为成功组和失败组,比较两组患者的年龄、上机前的APACHE II评分和意识水平以及上机前后的pH值及PaCO2值。结果两组中B iPAP呼吸机治疗后1h的pH值、PaCO2值比较有统计学意义(P<0.05),其它观察指标均无统计学意义(P>0.05)。结论B iPAP呼吸机治疗后1h的pH值、PaCO2值,是预测早期疗效的较好指标,若二者无改善,应考虑及时插管行有创通气治疗。Objective To investigate the early predictive indexes of curative effect of acute respiratory failure （AFR） treated with noninvasive bilevel positive airway pressure（BiPAP） ventilation. Methods Sixty -eight patients with AFR were treated with BiPAP ventilation. According to the therapeutic outcome, patients were divided into success group and failure group, and the distributions of ages, acute physiology and chronic health evaluation （APACHE Ⅱ ） score, consciousness level as well as arterial blood gas（ABG） measurement before and after the treatment with BiPAP ventilation were compared between the two groups. Results There was statistical difference in the ABG levels of pH and PaCO2 after 1 hour’s treatment with BiPAP ventilation（ P〈0. 05 ） and other indexes didnl show much differences（ P〉0.05）. Conclusion The levels of pH and PaCO2 after 1 hour＇s treatment with BiPAP ventilation are valuable markers for curative effects in early stadge. If the levels of pH and PaCO2 fail to improve, the treatment with intubation may be necessary.

关 键 词：急性呼吸衰竭 无创机械通气 疗效 

分 类 号：R563.8[医药卫生—呼吸系统] R135.1[医药卫生—内科学]