高血压患者生存质量评价  

Evaluation of quality of life of hypertensive patients

作　　者：陈英 王声涌[2] 池桂波[2] 喻侠华 洪城 李安荣 

机构地区：[1]广州越秀区第一人民医院心内科,广东广州510120 [2]暨南大学医学院流行病学教研室,广东广州510632 [3]广州越秀区第一人民医院,广东广州510030

出　　处：《第一军医大学学报》2005年第11期1387-1389,共3页Journal of First Military Medical University

基　　金：广东省医学科研项目(A2001603);越秀区科技计划项目(越2001-02)~~

摘　　要：目的探讨高血压患者生存质量(QOL)。方法采用世界卫生组织QOL(WHOQOL)-100量表,对319例高血压患者和正常对照人群进行生存质量测量,比较病例组与对照组的生存质量差异。结果高血压患者生存质量在身体机能、心理状况、独立能力、社会关系、生活环境、个人信仰各领域及QOL-100总评分方面皆显著低于正常对照组人群(P<0.01);调整了其他疾病的混杂作用后,除个人信仰领域外,高血压患者其他各领域及QOL-100总评分方面仍皆低于对照组(P<0.01)。HotellingT2检验及多元方差分析显示,高血压患者与对照组人群的生存质量从6个领域综合来看,具有显著性差异(P<0.01)。结论在有效降压的同时,积极改善患者的生存质量是临床抗高血压治疗的基本目标。Objective To evaluate the quality of life （QOL） of patients with hypertension. Methods Totally 319 patients with hypertension were investigated for their QOL in comparison with 319 healthy controls using the World Health Organization Quality of Life assessment instrument （WHOQOL-100）. Results The scores of physical functions, psychological condition, independent ability, social relation, living environment, and personal faith and the total score of QOL-100 were significantly lower in the hypertensive patients than in the normal subjects （P〈0.01）. Afier adjusting the confounding factors ofother diseases, the scores of all the items with the exception of personal faith and the total score of QOL-100 were all lower in the patients than in the controls （P〈0.01）. Hostelling T2 test and multivariate analysis of variance showed significant differences in the QOL between the hypertensive patients and the controls in the 6 domains synthesized （P〈0.01）, further demonstrating lowered QOL of hypertensive patients in comparison with the healthy population. Conclusion Improvement of the hypertensive patients＇ QOL in addition to effective blood pressure control is a basic target in clinical therapy of hypertension.

关 键 词：高血压 生存质量 统计分析 

分 类 号：R544.1[医药卫生—心血管疾病]