模拟酶的研究与发展  

Research and Progress of Mimetic Enzymes

作　　者：刘有芹[1] 颜芸[1] 沈含熙[2] 

机构地区：[1]华南农业大学理学院应用化学系,广州510642 [2]南开大学化学学院,天津300071

出　　处：《化学进展》2005年第6期1067-1073,共7页Progress in Chemistry

基　　金：国家自然科学基金资助项目(No.20075012);华南农业大学校长科学基金资助项目(No.K05053)

摘　　要：本文详细评述了卟啉、主体试剂、印迹高分子、膜体系及配合物等作为模拟酶的研究和发展。阐明了开展模拟酶的研究对于了解酶的作用机理、发展新型生物活性分子分析方法、探讨生物体系的生命现象的重要意义。对模拟酶研究的未来作了展望。The research progress of porphyrin, host reagent, imprinting polymer, membrane system and complexes as mimetic enzymes are reviewed in detail. It is of importance to develop the investigation of mimetic enzyme, which helps to understand the interacting mechanism of enzymes, establish the analytic methods of new bioactive molecules and make a deep insight into many important events in vivo. The future development of mimetic enzyme is prospected.

关 键 词：模拟酶 卟啉 主体试剂 印迹高分子 膜体系 配合物 

分 类 号：O629.8[理学—有机化学] O643.3[理学—化学]