我院127例左氧氟沙星注射液不良反应及用药监护  

127 Cases of Adverse Drug Reaction of Levofloxacin and Monitoring Administration

作　　者：张良海[1] 

机构地区：[1]南京大学医学院附属鼓楼医院药剂科,南京市210008

出　　处：《中国药房》2005年第22期1732-1734,共3页China Pharmacy

摘　　要：目的:探讨左氧氟沙星注射液致不良反应的一般规律及特点,为临床合理用药提供参考。方法:采用回顾性调查方法,对我院2004年填报的127例左氧氟沙星注射液致不良反应报告进行统计、分析。结果:不良反应临床表现主要以皮肤及附件损害、消化系统损害、静脉炎最常见;过敏性休克、跟腱炎、肝损害虽少见,但程度严重。结论:临床应重视合理使用左氧氟沙星注射液及其用药监护,以预防和减少不良反应的发生。OBJECTIVE： To discuss the features of adverse drug reactions（ADRs） of levofloxacin injection in order to provide the reference for rational drug use in clinic, METHODS： A retrospective investigation was carried out to analyze statistically. 127 reported cases of ADRs of levofloxacin in our hospital in 2004. RESULTS： The main ADRs of levofloxacin were mainly manifested as skin lesion, digestive system injury and phlebitis, Furthermore, anaphylactic shock, achilles tendonitis, and hepatic lesion were rare but severe adverse reactions, CONCLUSION： Rational use of levofloxacin injection and monitoring of its administration should be emphasized in clinic for the prevention and reduction in occurrence of ADRs.

关 键 词：左氧氟沙星注射液 不良反应 用药监护 

分 类 号：R978.21[医药卫生—药品]