米非司酮配伍依沙吖啶用于初孕中期妊娠引产58例临床总结  

作　　者：孙桂英[1] 李丽[1] 

机构地区：[1]中国人民解放军第401医院妇产科,青岛266071

出　　处：《中华当代医学》2005年第11期16-17,共2页Chinese Modern Medicine

摘　　要：目的比较米非司酮片配伍乳依沙吖啶羊膜腔内注射引产法和乳酸依沙吖啶羊膜腔内注射引产法在初孕中期妊娠引产中的效果。方法将108例自愿要求终止妊娠、无引产禁忌症的初孕健康妇女随机分为两组，观察组58例，口服米非司酮片50mg，12小时后加服25mg，同时予以乳酸依沙吖啶100mg羊膜腔内注射；对照组：乳酸依沙吖啶100mg羊膜腔内注射。结果观察组产程明显短于对照组，产后出血量、清宫率明显低于对照组，统计学处理有显著性差异（P〈0．05）；两组均具有较高的成功率和安全性，在平均住院日方面无统计学差异。结论米非司酮片配伍乳酸依沙吖啶羊膜腔内注射引产法优于单纯乳酸依吵吖啶羊膜腔内注射法。Objective To observe the effect of Mifepristone tablet complicated Ethacridine Lactate instilled into the amniotic sac and Ethacrine Lactate instilled into the amniotic sac on the second-trimester of pregnancy in pregnancy in primigravidae. Methods 108 healthy primigravidae who want to terminate pregnancy without contraindication for inducation of labor were divided randomly into two groups. 58 cases who were treated with Mifepristone tablet complicated Ethacridine Lactate as the observed group. 50 cases who were treated only with Etheacridine Lactate as the control group. Results The durations of labors in the observed group were markedly shorter than in the control group, the amount of postpartum heamorrhage and the rate of uterine curettings were lower in the former than in the latter. Statistic results show notable differences betweet the two groups（P〈0.05）. The successful rate and safety were rather high and the average days during which patients stayed in hospital have no notable differences by Statistic test in both groups. Conclusion The method of Mifepristone tablet complicated Ethacridine lactate instilled into the amniotic sac is more practicable than only Ethacridine Lactate instilled into the amniotic sac.

关 键 词：米非司酮片 乳酸依沙吖啶 中期妊娠 引产 

分 类 号：R927.2[医药卫生—药学] R169.42