TS90%评估阻塞性睡眠呼吸暂停低通气综合征低氧血症程度的临床价值  

Clinical value of TS90% in evaluation of hypoxemia in patients with obstructive sleep apnea /hypoventilation syndrome

作　　者：李进让[1] 孙建军[1] 章榕[1] 李春风[1] 胡燏[1] 孙玉梅[1] 

机构地区：[1]海军总医院全军耳鼻咽喉科中心,北京100037

出　　处：《中华医学杂志》2005年第44期3115-3117,共3页National Medical Journal of China

摘　　要：目的探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者低氧血症程度的判断指标。方法分析经多导睡眠呼吸监测仪诊断的108例OSAHS患者和37例单纯鼾症的多导睡眠监测资料。参照杭州会议诊断标准,计算最低血氧饱和度(M iO2)和血氧饱和度<90%时间占监测总时间的百分比(TS90%)与呼吸暂停低通气指数(AH I)的相关系数。结果随OSAHS严重程度的增高,TS90%数值也逐渐增高,而M iO2值逐渐下降(TS90%、M iO2在单纯鼾症、轻度OSAHS、中度OSAHS、重度OSAHS分别为1.47、82.00,4.23、80.00,12.85、74.00,37.82、62.00),差异有统计学意义(均P<0.001)。TS90%与AH I和患者主观感觉嗜睡分值(ESS)的相关性均高于M iO2。结论TS90%能较为客观地反映患者睡眠时低氧血症的严重程度,与M iO2相参照则能整体地、客观地反映患者的缺氧程度。Objective To explore the appropriate study how to properly evaluate the hypoxemia degree in patients with obstructive sleep apnea/hypoventilation syndrome （OSAHS）. Methods pelysomnography was conducted on 108 OSAHS patients and 37 simple snorers to record the minimum oxygen saturation level （ MiO2 ） and the total recorded time spent below 90% oxygen saturation （ TS90% ）. The correlation between MiO2 and the percent of the total recorded time spent below 90% oxygen saturation （TS90%） with the AHI were calculated. Results The value of TS90% was significantly increased, and the value of MiO2 was significantly decreased as the severity of OSAHS increased （ all P 〈 0. 001 ）. The correlation coefficients of TS90% with AHI and with Epworth sleepiness scale （ESS） were both much higher than those of MiO2. Conclusion TS90% can express the severity of hypoxemia of the OSAHS patients more correctly than MiO2. TS90% combined with MiO2 can comprehensively and objectively reflect the severity of hypoxia of the OSAHS patients.

关 键 词：睡眠呼吸暂停综合征 低氧血 多导睡眠监测 

分 类 号：R766[医药卫生—耳鼻咽喉科]