基于造影图像的冠状动脉三维定量分析的研究  

Study on 3-D Quantitative Analysis of Coronary Artery Based on Angiogram

作　　者：胡春红[1] 郁道银[1] 黄家祥[1] 李伟锋[1] 

机构地区：[1]天津大学精密仪器与光电子工程学院光电信息技术科学教育部重点实验,天津300072

出　　处：《光电子．激光》2005年第11期1386-1390,共5页Journal of Optoelectronics·Laser

基　　金：国家自然科学基金资助项目(30500129);高等学校博士学科点专项科研基金资助项目(20030056018);中国博士后科学基金资助项目(2004036361)

摘　　要：由于X射线造影成像把血管三维空间结构投影到二维图像上,基于二维造影图像的传统诊治方法存在很大局限性。本文在冠状动脉树三维重建的基础上,研究了冠状动脉的三维定量分析方法,提出血管直径、分支夹角和血管段长度的三维测量方法。并利用冠状动脉树实物模型进行实验,对二维和三维定量分析结果进行了比较。实验结果表明,三维定量分析能够有效地提高临床医学参数的测量精度。因此,在冠心病的临床诊断和介入治疗中,该方法能够可靠地诊断血管狭窄及选择和放置支架。Coronary angiography is regarded as the “gold standard” for the assessment of coronary artery disease. However, coronary angiography is limited by its two-dimensional （2-D） representation of three-dimensional （3-D） structures. Based on 3-D reconstruction of coronary arterial tree, a method was proposed to calculate the 3-D values of diameter, length,and branch angle in 3-D quantitative coronary angiography （QCA）. 2-D QCA and 3- D QCA were compared in the accuracy of quantification using images of vessel phantom. The experiments show 3-D QCA can get more accurate results. Therefore, 3-D QCA using the proposed method is capable of the reliable assessment of stenosis or selection and placement of stents durina diaanostic and interventional procedures.

关 键 词：冠状动脉 三维定量分析 直径 长度 分支夹角 

分 类 号：R318.51[医药卫生—生物医学工程]