实弹射击考核对不同特质焦虑新兵T淋巴细胞亚群及ACTH的影响  

The Subtype of T Lymphocytes and ACTH Changes in Different Trait-anxiety Levels of New Recruits Under Ball Firing Examination

作　　者：李川云[1] 程灵芝[2] 刘晓红[2] 邓光辉[2] 严进[2] 陈瑶[2] 

机构地区：[1]南京政治学院上海分院军事心理系,上海200433 [2]第二军医大学心理学教研室,上海200433

出　　处：《中国临床心理学杂志》2005年第4期477-479,共3页Chinese Journal of Clinical Psychology

基　　金：全军医药科研"十五"指令性课题(项目号:PLA1001121);第二军医大学军事课题(项目号:2001J-2)

摘　　要：目的:研究急性应激对不同特质焦虑新兵的T淋巴细胞亚群及ACTH的影响。方法:状态-特质焦虑问卷(STAI)将新兵分成高、低特质焦虑组各16人。用流式细胞仪及ELISA测定被试基础期(打靶前4d)、应激期(打靶时)、恢复期(打靶后5d)的CD4+、CD8+及ACTH浓度。结果:①高特质组3个时期的CD4+、CD4+/CD8+比值均低于低特质组,CD8+高于低特质组;高特质组应激期CD4+显著下降(P<0.05)、CD4+/CD8+比值与恢复期有显著差异(P<0.01),而低特质组仅应激期CD4+定量与恢复期有显著差异(P<0.01)。②实弹射击前、中、后的ACTH浓度,高特质组变化呈极显著差异(P<0.001),而低特质组应激期与基础期呈显著差异(P<0.05)。结论:①急性应激影响新兵的CD4+、CD8+及其比值,其程度与特质焦虑有关。②应激时高特质组ACTH浓度下降显著大于低特质组,且随应激源消除不易恢复。Objective： To study changes of subtype of T lymphocytes and ACTH in different trait-anxiety levels of new recruits under acute stress. Methods： Subjects were divided into high trait-anxiety and low anxiety group （each 16 ） by state-trait anxiety inventory. CD4^＋ and CD8^＋ and ACTH were tested in pre-stress （4d before exam.）, stress （under exam.） and post-stress （Sd after military exam.） phases by FCM and ELISA. Results： ①CD4^＋,CD4^＋/CD8^＋ of the high trait group in the three phases were lower than those in the low trait-auxiety group, and its CD8^＋ was higher than that in the low-trait anxiety group, and CD4^＋ of the high trait-anxiety group was higher than that in the low trait-anxiety group; CD4^＋ of the high trait-anxiety group under stress were significantly decreased （P〈0.05）, and the CD^4/CD8^＋ was obviously different as compared with that in the post-stress phase; while only CD4^＋ quantity of the low trait-anxiety group of the stress phase was different from that in the post stress phase（P〈0.01）.②The ACTH in high trait-anxiety group was significantly different in three phases （P〈0.001）, but in low trait-anxiety group it was only significantly different between pre-stress and stress. Conclusion： ①Acute stress can affect the amounts of subtype T lymphocytes in subjects, which is related to individual trait-anxiety score.② Compared with low trait-anxiety group, ACTH is more sensitive under stress and more difficult to restore as stressors withdraw in high trait-anxiety group.

关 键 词：急性心理应激 新兵 促肾上腺皮质激素 T淋巴细胞亚群 

分 类 号：R395.6[哲学宗教—心理学]