两种百白破联合疫苗接种安全性比较  

Comparison on the Safety of Two kinds of DTP Vaccines

作　　者：王琦[1] 王孟杰[1] 王飞[1] 

机构地区：[1]山东省滨州市疾病预防控制中心,256618

出　　处：《职业与健康》2005年第12期1986-1987,共2页Occupation and Health

摘　　要：目的了解全细胞百白破疫苗(DTwP)与无细胞百白破疫苗(DTaP)在婴儿群体中接种后的安全性. 方法对3～6月龄的婴儿及18～24月龄的幼儿进行了两种疫苗接种后安全性的临床观察.结果基础免疫接种DTwP后全身反应发生率17.65%,局部反应发生率 18.74%;接种DTaP全身、局部反应发生率均为2.05%.加强免疫接种DTwP后全身反应发生率为35.52%,局部反应发生率为30.36%;接种DTaP后全身反应发生率5.15%,局部反应发生率为 6.24%.结论表明DTaP有更好的安全性.[Objective] To learn the safety of DTwp and DTap vaccines on babies. [Methods] Two kinds of vaccines were inoculated among babies; clinical observation was made on the safety of the two vaccines. [Results] The whole- body reaction rate and partial reaction rate of DTwP were 17.65% and 18.74% respectively; that of the DTaP were both 2.05% ; that of the intensive immunization DTwP were 35.52% and 30.36% respectively; that of the intensive DTaP were 5.15% and 6.24% respectively. [Conclusion] It is proved that DTAP is safer than DTwP.

关 键 词：全细胞百白破联合疫苗 无细胞百白破联合疫苗 安全性 

分 类 号：R186.3[医药卫生—流行病学]